Molecular Basis of Ubiquitination Catalyzed by the Bacterial Transglutaminase MavC
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Science"
DOI: 10.1002/advs.202000871
Abstract: Abstract The Legionella pneumophila effector MavC is a transglutaminase that carries out atypical ubiquitination of the host ubiquitin (Ub)‐conjugation enzyme UBE2N by catalyzing the formation of an isopeptide bond between Gln40Ub and Lys92UBE2N, which leads… read more here.
Keywords: mavc; transglutaminase; molecular basis; basis ubiquitination ... See more keywords
Molecular Basis for Chemoselectivity Control in Oxidations of Internal Aryl‐Alkenes Catalyzed by Laboratory Evolved P450s
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DOI: 10.1002/cbic.202400066
Abstract: P450 enzymes naturally perform selective hydroxylations and epoxidations of unfunctionalized hydrocarbon substrates, among other reactions. The adaptation of P450 enzymes to a particular oxidative reaction involving alkenes is of great interest for the design of… read more here.
Keywords: laboratory; basis chemoselectivity; chemoselectivity; chemoselectivity control ... See more keywords
Unraveling the Molecular Basis for G‐Quadruplex‐Binders to ALS/FTD‐Associated G4C2 Repeats of the C9orf72 Gene
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DOI: 10.1002/cbic.202400974
Abstract: The most recurrent familial cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) is the presence of an abnormal number of intronic GGGGCC (G4C2) repetitions in the C9orf72 gene, which has been proposed to… read more here.
Keywords: molecular basis; c9orf72 gene; als ftd; g4c2 ... See more keywords
Molecular basis underlying default mode network functional abnormalities in postpartum depression with and without anxiety
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DOI: 10.1002/hbm.26657
Abstract: Although Postpartum depression (PPD) and PPD with anxiety (PPD‐A) have been well characterized as functional disruptions within or between multiple brain systems, however, how to quantitatively delineate brain functional system irregularity and the molecular basis… read more here.
Keywords: ppd; postpartum depression; brain; ppd ppd ... See more keywords
Recent advances in the design of choline kinase α inhibitors and the molecular basis of their inhibition
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DOI: 10.1002/med.21746
Abstract: Upregulated choline metabolism, characterized by an increase in phosphocholine (PCho), is a hallmark of oncogenesis and tumor progression. Choline kinase (ChoK), the enzyme responsible for PCho synthesis, has consequently become a promising drug target for… read more here.
Keywords: chok inhibitors; molecular basis; recent advances; choline kinase ... See more keywords
Molecular basis of quinine-induced feeding suppression in Hyphantria cunea larvae.
Sign Up to like & getrecommendations! Published in 2025 at "Pest management science"
DOI: 10.1002/ps.70268
Abstract: Feeding behavior in herbivorous insects is profoundly influenced by chemical cues present in their environment, with some compounds serving as deterrents that reduce or completely inhibit feeding. The fall webworm, Hyphantria cunea, is a highly… read more here.
Keywords: hyphantria cunea; induced feeding; quinine induced; feeding suppression ... See more keywords
Methods to Investigate the Molecular Basis of Progranulin Action on Neurons In Vivo Using Caenorhabditis elegans.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8559-3_13
Abstract: The C. elegans nematode is a powerful genetic tool for the study of aging, developmental biology, and neurodegenerative diseases. They are a small and simple model, but its well-known genome and presence of many human… read more here.
Keywords: molecular basis; biology; investigate molecular; basis progranulin ... See more keywords
Molecular Basis and Regulation of Store-Operated Calcium Entry.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-12457-1_17
Abstract: Store-operated Ca2+ entry (SOCE) is a ubiquitous mechanism for Ca2+ influx in mammalian cells with important physiological implications. Since the discovery of SOCE more than three decades ago, the mechanism that communicates the information about… read more here.
Keywords: store operated; molecular basis; basis regulation; ca2 ... See more keywords
The genetic and molecular basis of crop height based on a rice model
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DOI: 10.1007/s00425-017-2798-1
Abstract: AbstractMain conclusionThis review presents genetic and molecular basis of crop height using a rice crop model. Height is controlled by multiple genes with potential to be manipulated through breeding strategies to improve productivity. Height is… read more here.
Keywords: genetic molecular; rice; molecular basis; model ... See more keywords
Molecular basis of triterpene-based chemophenetics in ferns
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DOI: 10.1007/s00425-020-03369-3
Abstract: Main conclusion A hypothesis that squalene cyclase genes are widely distributed throughout ferns was proposed. We successfully isolated a squalene cyclase pseudogene from a fern from which no triterpene hydrocarbons were detected Abstract Ferns are… read more here.
Keywords: triterpene based; basis triterpene; triterpene; molecular basis ... See more keywords
Molecular basis of autism spectrum disorders
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DOI: 10.1007/s11033-025-10604-1
Abstract: Autism is a prevalent neurological disorder that affects the development of children worldwide. With the advent of genome wide association studies and whole exome sequencing methods, associated genes and molecular pathways that lead to the… read more here.
Keywords: basis autism; autism spectrum; molecular pathways; molecular basis ... See more keywords