A Facile Strategy to Enhance Specificity and Sensitivity of Molecular Beacons by an Aptamer Functionalized Delivery Vector.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b04596
Abstract: To enhance the specificity and sensitivity of molecular beacons (MB) in detecting mRNA in living tumor cells, we introduced an aptamer (AS1411) to the delivery system of MB to form aptamer decorated nanoprobe (ANP), which… read more here.
Keywords: molecular beacons; delivery; tumor cells; specificity sensitivity ... See more keywords
Supramolecular Microgels with Molecular Beacons at the Interface for Ultrasensitive, Amplification-Free, and SNP-Selective miRNA Fluorescence Detection.
Sign Up to like & getrecommendations! Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.8b22635
Abstract: In this study, a supramolecular structure with femtomolar biorecognition properties is proposed for use in analytical devices. It is obtained by an innovative interface between synthetic hydrogel polymers and molecular beacon (mb) probes. Supramolecularly structured… read more here.
Keywords: detection; molecular beacons; microgels molecular; beacons interface ... See more keywords
Fluorinated molecular beacons as functional DNA nanomolecules for cellular imaging††Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc02819a Click here for additional data file.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical Science"
DOI: 10.1039/c7sc02819a
Abstract: Molecular beacons (MBs) are simple, but practical, fluorescent nanoprobes widely used to detect small molecules, nucleic acids and proteins. read more here.
Keywords: nanomolecules cellular; fluorinated molecular; molecular beacons; functional dna ... See more keywords
Molecular beacons with oxidized bases report on substrate specificity of DNA oxoguanine glycosylases
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d1sc05648d
Abstract: DNA glycosylase enzymes recognize and remove structurally distinct modified forms of DNA bases, thereby repairing genomic DNA from chemically induced damage or erasing epigenetic marks. However, these enzymes are often promiscuous, and advanced tools are… read more here.
Keywords: dna; molecular beacons; beacons oxidized; specificity ... See more keywords
Detection of SARS-CoV-2 RNA using RT-LAMP and molecular beacons
Sign Up to like & getrecommendations! Published in 2021 at "Genome Biology"
DOI: 10.1186/s13059-021-02387-y
Abstract: Background Rapid spread of SARS-CoV-2 has led to a global pandemic, resulting in the need for rapid assays to allow diagnosis and prevention of transmission. Reverse transcription-polymerase chain reaction (RT-PCR) provides a gold standard assay… read more here.
Keywords: lamp beac; cov rna; molecular beacons; detection sars ... See more keywords
Extracellular mRNA detected by molecular beacons in tethered lipoplex nanoparticles for diagnosis of human hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0198552
Abstract: Hepatocellular carcinoma (HCC) remains one of the major causes of cancer related deaths. Although ultrasonography (US), computed tomography (CT) and/or high-cost magnetic resonance imaging (MRI) have been shown to improve early detection of liver cancer… read more here.
Keywords: hepatocellular carcinoma; molecular beacons; hcc; tethered lipoplex ... See more keywords