A stony coral cell atlas illuminates the molecular and cellular basis of coral symbiosis, calcification, and immunity
Sign Up to like & getrecommendations! Published in 2021 at "Cell"
DOI: 10.1016/j.cell.2021.04.005
Abstract: Summary Stony corals are colonial cnidarians that sustain the most biodiverse marine ecosystems on Earth: coral reefs. Despite their ecological importance, little is known about the cell types and molecular pathways that underpin the biology… read more here.
Keywords: molecular cellular; cellular basis; coral cell; biology ... See more keywords
The Immunological Organ Environment Dictates the Molecular and Cellular Pathways of Cytotoxic Antibody Activity.
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.10.111
Abstract: Cytotoxic immunoglobulin G antibodies are an essential component of therapeutic approaches aimed at depleting self-reactive or malignant cells. More recent evidence suggests that the tissue in which the target cell resides influences the underlying molecular… read more here.
Keywords: cytotoxic antibody; molecular cellular; cellular pathways; antibody activity ... See more keywords
Molecular and cellular mechanisms of chemoresistance in pancreatic cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in biological regulation"
DOI: 10.1016/j.jbior.2017.11.007
Abstract: Pancreatic Ductal Adenocarcinoma (PDAC) is one of the most chemoresistant cancers, and current therapies targeting cancer-associated molecular pathways have not given satisfactory results, owing in part to rapid upregulation of alternative compensatory pathways. Most of… read more here.
Keywords: molecular cellular; cellular mechanisms; pancreatic cancer; cancer ... See more keywords
APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types
Sign Up to like & getrecommendations! Published in 2018 at "Neuron"
DOI: 10.1016/j.neuron.2018.06.011
Abstract: (Neuron 98, 1141–1154; June 27, 2018) An erroneous panel was included in Figure 6 in a previous version of this paper. The representative image of mEPSC recording traces shown in Figure 6A was not correct… read more here.
Keywords: molecular cellular; causes widespread; figure; widespread molecular ... See more keywords
Molecular and cellular genetics of non-Hodgkin lymphoma: Diagnostic and prognostic implications.
Sign Up to like & getrecommendations! Published in 2019 at "Experimental and molecular pathology"
DOI: 10.1016/j.yexmp.2018.11.008
Abstract: Non-Hodgkin lymphoma (NHL) is a diverse collection of malignant neoplasms with lymphoid-cell origin which includes all the malignant lymphomas that are not classified as Hodgkin lymphoma. NHL is one of the most common types of… read more here.
Keywords: lymphoma; molecular cellular; hodgkin lymphoma; cellular genetics ... See more keywords
Advancing Ultrasensitive Molecular and Cellular Analysis Methods to Speed and Simplify the Diagnosis of Disease.
Sign Up to like & getrecommendations! Published in 2017 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.6b00497
Abstract: Diagnosing disease at the molecular level rapidly and with a high level of sensitivity and specificity is a critical capability for modern medicine. Rapid detection of small numbers of biomarkers of early disease in complex,… read more here.
Keywords: molecular cellular; cellular analysis; disease; ultrasensitive molecular ... See more keywords
Molecular and Cellular Mechanisms of Neuropathic Pain in Aging.
Sign Up to like & getrecommendations! Published in 2023 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.3c00010
Abstract: Neuropathic pain is a chronic condition that tends to worsen over time, leading to a significant decline in patients' quality of life. The elderly population is disproportionately affected by this burden, as evidenced by the… read more here.
Keywords: pain aging; mechanisms neuropathic; cellular mechanisms; neuropathic pain ... See more keywords
Molecular and cellular signatures underlying superior immunity against Bordetella pertussis upon pulmonary vaccination
Sign Up to like & getrecommendations! Published in 2018 at "Mucosal Immunology"
DOI: 10.1038/mi.2017.81
Abstract: Mucosal immunity is often required for protection against respiratory pathogens but the underlying cellular and molecular mechanisms of induction remain poorly understood. Here, systems vaccinology was used to identify immune signatures after pulmonary or subcutaneous… read more here.
Keywords: molecular cellular; immunity; cellular signatures; bordetella pertussis ... See more keywords
Molecular and cellular determinants of motor asymmetry in zebrafish
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-14965-y
Abstract: Asymmetries in motor behavior, such as human hand preference, are observed throughout bilateria. However, neural substrates and developmental signaling pathways that impose underlying functional lateralization on a broadly symmetric nervous system are unknown. Here we… read more here.
Keywords: left right; molecular cellular; motor asymmetry; motor ... See more keywords
Molecular and cellular insight into Escherichia coli SslE and its role during biofilm maturation
Sign Up to like & getrecommendations! Published in 2022 at "NPJ Biofilms and Microbiomes"
DOI: 10.1038/s41522-022-00272-5
Abstract: Escherichia coli is a Gram-negative bacterium that colonises the human intestine and virulent strains can cause severe diarrhoeal and extraintestinal diseases. The protein SslE is secreted by a range of pathogenic and commensal E. coli… read more here.
Keywords: molecular cellular; maturation; biofilm maturation; escherichia coli ... See more keywords
Molecular and cellular cues governing nanomaterial-mucosae interactions: from nanomedicine to nanotoxicology.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Society reviews"
DOI: 10.1039/c8cs00948a
Abstract: Mucosal tissues constitute the largest interface between the body and the surrounding environment and they regulate the access of molecules, supramolecular structures, particulate matter, and pathogens into it. All mucosae are characterized by an outer… read more here.
Keywords: molecular cellular; governing nanomaterial; nanomedicine nanotoxicology; cellular cues ... See more keywords