Application of NGS molecular classification in the diagnosis of endometrial carcinoma: A supplement to traditional pathological diagnosis
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5363
Abstract: This study aims to demonstrate the advantages of NGS molecular classification in EC diagnosis and to assess whether molecular classification could be performed on curettage specimens and its concordance with subsequent hysterectomy specimens. read more here.
Keywords: molecular classification; classification diagnosis; diagnosis; application ngs ... See more keywords
Gastric cancer molecular classification and adjuvant therapy: Is there a different benefit according to the subtype?
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.25792
Abstract: Gastric cancer (GC) has been defined in distinct molecular subtypes with different therapeutic implications. However, its clinical significance and prognosis regarding standard chemotherapy (CMT) remains unclear. This study aimed to analyze the impact of perioperative… read more here.
Keywords: molecular classification; gastric cancer; classification adjuvant; cancer ... See more keywords
Extent of Resection Versus Molecular Classification: What Matters When?
Sign Up to like & getrecommendations! Published in 2019 at "Neurosurgery clinics of North America"
DOI: 10.1016/j.nec.2018.08.006
Abstract: For malignant gliomas, the survival benefit of new combination therapies after surgical resection is measured in weeks to months. In contrast, optimizing treatment for low-grade gliomas can potentially provide additional years of life. The relatively… read more here.
Keywords: molecular classification; extent resection; versus molecular; resection versus ... See more keywords
Molecular classification of breast cancer: what the pathologist needs to know.
Sign Up to like & getrecommendations! Published in 2017 at "Pathology"
DOI: 10.1016/j.pathol.2016.10.012
Abstract: Breast cancer is a heterogeneous disease featuring distinct histological, molecular and clinical phenotypes. Although traditional classification systems utilising clinicopathological and few molecular markers are well established and validated, they remain insufficient to reflect the diverse… read more here.
Keywords: molecular classification; classification breast; breast; breast cancer ... See more keywords
Molecular classification of pulmonary sarcomatoid carcinomas suggests new therapeutic opportunities
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Oncology"
DOI: 10.1093/annonc/mdx162
Abstract: Background Pulmonary sarcomatoid carcinoma (SC) is a rare disease with poor prognosis and with strong inter- and intratumor heterogeneity. However, molecular classification is currently focused on activating MET mutations. We sought to better characterize the… read more here.
Keywords: molecular classification; classification; series; pulmonary sarcomatoid ... See more keywords
Molecular classification of IDH-mutant glioblastomas based on gene expression profiles
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DOI: 10.1093/carcin/bgz032
Abstract: Abstract Isocitrate dehydrogenase (IDH) mutant glioblastoma (GBM), accounts for ~10% GBMs, arises from lower grade diffuse glioma and preferentially appears in younger patients. Here, we aim to establish a robust gene expression-based molecular classification of… read more here.
Keywords: molecular classification; ontology; idh mutant; gene expression ... See more keywords
LINC-03. MOLECULAR CLASSIFICATION OF PAEDIATRIC MEDULLOBLASTOMA FROM FOUR TERTIARY CENTRES IN MALAYSIA: DIAGNOSTIC DILEMMA WITH CONVENTIONAL METHODS
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaa222.438
Abstract: Abstract OBJECTIVE To determine the prognostic significance of the four molecular subgroups of medulloblastoma (MB) among children in Malaysia. METHODS We assembled MB samples of children < 18 years between January 1999 and July 2017… read more here.
Keywords: molecular classification; paediatric medulloblastoma; classification paediatric; methylation profiling ... See more keywords
P10.15 Molecular Classification of Malignant Glioma
Sign Up to like & getrecommendations! Published in 2017 at "Neuro-oncology"
DOI: 10.1093/neuonc/nox036.333
Abstract: Background: Malignant glioma are devastating tumors with poor prognosis. In recent years, the classification of glioma have evolved greatly due to exploration of several molecular tools in addition ... read more here.
Keywords: molecular classification; glioma; classification malignant; malignant glioma ... See more keywords
A molecular classification of moles and its use in filiation tests.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of forensic sciences"
DOI: 10.1111/1556-4029.14890
Abstract: Pregnancies, including ones that follow sexual assaults, occasionally produce hydatidiform moles. The alleged fathers (AFs) of moles have been tested for paternity by identifying the mole's locus phenotype-the one or two visible paternal obligate alleles… read more here.
Keywords: use filiation; molecular classification; classification moles; moles use ... See more keywords
Influence of molecular classification in anaplastic glioma for determining outcome and future approach to management
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Medical Imaging and Radiation Oncology"
DOI: 10.1111/1754-9485.12850
Abstract: Assess survival of patients with anaplastic glioma (AG) and the relationship to molecular subtype. read more here.
Keywords: anaplastic glioma; molecular classification; glioma; glioma determining ... See more keywords
Incorporating molecular profiling into endometrial cancer management requires prospective studies
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2021-002705
Abstract: Molecular profiling of endometrial carcinoma according to The Cancer Genome Atlas (TCGA) points toward a paradigm shift from morphological to molecular classification. TCGA and many subsequent studies confirm the existence of four specific types of… read more here.
Keywords: molecular classification; carcinoma; molecular profiling; endometrial carcinoma ... See more keywords