Assembly of Molecular Complexity by Carbene Organocatalytic Multi‐component Reactions involving α,β‐Unsaturated Aldehydes
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.202500220
Abstract: The pursuit of molecular complexity is central to modern organic synthesis, as complex molecules are essential across various fields. The development of catalytic multi‐component transformation strategies provides an efficient approach for the rapid and selective… read more here.
Keywords: component reactions; multi; molecular complexity; involving unsaturated ... See more keywords
Exploring Molecular Complexity by N-Heterocyclic Carbene Organocatalysis: New Activation and Reaction Diversity.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical record"
DOI: 10.1002/tcr.202200219
Abstract: The development of catalytic synthetic approaches towards molecular complexity from simple materials continues to be an ultimate goal in synthetic chemistry. Over the past decades, N-heterocyclic carbene (NHC) organocatalysis has been extensively investigated to provide… read more here.
Keywords: new activation; molecular complexity; organocatalysis; complexity ... See more keywords
Costly circRNAs, Effective Population Size, and the Origins of Molecular Complexity.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of molecular evolution"
DOI: 10.1007/s00239-021-10033-1
Abstract: While much excitement has attended the discovery and study of circular RNAs, a new study in Cell Reports suggests that most mammalian circRNAs are not only functionless, but in fact costly. Comparison across three species is… read more here.
Keywords: molecular complexity; hypothesis; drift barrier; effective population ... See more keywords
A View on Molecular Complexity from the GDB Chemical Space
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Chemical Information and Modeling"
DOI: 10.1021/acs.jcim.5c00334
Abstract: One recurring question when choosing which molecules to select for investigation is that of molecular complexity: is there a price to pay for complexity in terms of synthesis difficulty, and does complexity have anything to… read more here.
Keywords: chemical space; complexity; molecular complexity; view molecular ... See more keywords
Organometallic chemistry: A shortcut to molecular complexity.
Sign Up to like & getrecommendations! Published in 2017 at "Nature chemistry"
DOI: 10.1038/nchem.2750
Abstract: A unique transformation for the site-selective cleavage of one C–C single bond and two C–H bonds in sequence has now been developed. This enables a simple carbon skeleton to be reorganized into a significantly more… read more here.
Keywords: shortcut molecular; chemistry; molecular complexity; organometallic chemistry ... See more keywords
The emergence of interstellar molecular complexity explained by interacting networks
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2119734119
Abstract: Significance The road to life is punctuated by transitions toward complexity, from astrochemistry to biomolecules and eventually, to living organisms. Disentangling the origin of such transitions is a challenge where the application of complexity and… read more here.
Keywords: interstellar molecular; explained interacting; molecular complexity; emergence interstellar ... See more keywords
Protonated molecular clusters: promoting molecular complexity
Sign Up to like & getrecommendations! Published in 2024 at "Physica Scripta"
DOI: 10.1088/1402-4896/ad9c34
Abstract: Molecules identified in Space display a diversity greater than ever, yet the mechanisms responsible for this complexity remain largely unknown. The extreme conditions faced by these molecules under astrophysical conditions raise several questions about their… read more here.
Keywords: clusters promoting; molecular clusters; complexity; promoting molecular ... See more keywords