DNA Molecular Computing with Weighted Signal Amplification for Cancer miRNA Biomarker Diagnostics
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202416490
Abstract: The expression levels of microRNAs (miRNAs) are strongly linked to cancer progression, making them promising biomarkers for cancer detection. Enzyme‐free signal amplification DNA circuits have facilitated the detection of low‐abundance miRNAs. However, these methods may… read more here.
Keywords: signal amplification; cancer; weighted signal; amplification ... See more keywords
Allosteric Nucleic Acid Enzyme: A Versatile Stimuli-Responsive Tool for Molecular Computing and Biosensing Nanodevices.
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DOI: 10.1002/smll.202300207
Abstract: Allostery is a naturally occurring mechanism in which effector binding induces the modulation and fine control of a related biomolecule function. Deoxyribozyme (DNAzyme) with catalytic activity and substrate recognition ability is ideal to be regulated by… read more here.
Keywords: stimuli responsive; allosteric nucleic; molecular computing; acid enzyme ... See more keywords
Molecular Computing and Bioinformatics
Sign Up to like & getrecommendations! Published in 2019 at "Molecules"
DOI: 10.3390/molecules24132358
Abstract: Molecular computing and bioinformatics are two important interdisciplinary sciences that study molecules and computers. Molecular computing is a branch of computing that uses DNA, biochemistry, and molecular biology hardware, instead of traditional silicon-based computer technologies.… read more here.
Keywords: biochemistry; chemistry; biology; computing bioinformatics ... See more keywords