Molecular-defined clonal evolution in patients with classical myeloproliferative neoplasms.
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DOI: 10.1111/bjh.18834
Abstract: Classical myeloproliferative neoplasms (MPNs) are characterized by distinct clinical phenotypes. The discovery of driver mutations in JAK2, CALR and MPL genes provided new insights into their pathogenesis. Next-generation sequencing (NGS) identified additional somatic mutations, most… read more here.
Keywords: defined clonal; molecular defined; clonal evolution; classical myeloproliferative ... See more keywords