Microscale Symmetrical Electroporator Array as a Versatile Molecular Delivery System
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep44757
Abstract: Successful developments of new therapeutic strategies often rely on the ability to deliver exogenous molecules into cytosol. We have developed a versatile on-chip vortex-assisted electroporation system, engineered to conduct sequential intracellular delivery of multiple molecules… read more here.
Keywords: system; symmetrical electroporator; molecular delivery; delivery ... See more keywords
A chemically encoded timer for dual molecular delivery at tailored ranges and concentrations.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical communications"
DOI: 10.1039/c8cc03253j
Abstract: Spatiotemporal control of molecular distribution is much in demand in many fields of chemistry. To address this goal, we exploit a low molecular weight branched self-immolative architecture, which acts as a triggerable chemically encoded timer… read more here.
Keywords: chemically encoded; encoded timer; molecular delivery; dual molecular ... See more keywords
Molecular Delivery of Cytotoxic Agents via Integrin Activation
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13020299
Abstract: Simple Summary Chemotherapy constituted a cornerstone in cancer treatment, but it suffers from non-selective drug cytotoxicity; an active drug targeting exerted by covalent conjugates between antitumor agents and some integrin ligands should have a more… read more here.
Keywords: cytotoxic; molecular delivery; covalent conjugates; cytotoxic agents ... See more keywords