Toward Rapid and Accurate Molecular Diagnostics at Home
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202206525
Abstract: The global outbreaks of infectious diseases have significantly driven an imperative demand for rapid and accurate molecular diagnostics. Nucleic acid amplification tests (NAATs) feature high sensitivity and high specificity; however, the labor‐intensive sample preparation and… read more here.
Keywords: diagnostics home; sample preparation; molecular diagnostics; accurate molecular ... See more keywords
Molecular diagnostics of infectious disease: Detection and characterization of microbial agents in cytology samples
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostic Cytopathology"
DOI: 10.1002/dc.25064
Abstract: Cytology samples are widely used to diagnose various infectious diseases by detection and identification of causative infectious agents, including bacteria, fungi, and viruses. The role of cytopathology in infectious disease has expanded tremendously in the… read more here.
Keywords: cytology samples; detection; cytology; infectious disease ... See more keywords
Advances in sarcoma molecular diagnostics
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.1002/gcc.23025
Abstract: Sarcomas are cancers of mesenchymal origin with the potential to arise in diverse anatomic locations. With over 80 subtypes, which often demonstrate overlapping morphologies, sarcomas frequently require ancillary testing to enable accurate classification. Pathognomonic driver… read more here.
Keywords: sarcoma molecular; molecular diagnostics; advances sarcoma;
Long‐read sequencing for molecular diagnostics in constitutional genetic disorders
Sign Up to like & getrecommendations! Published in 2022 at "Human Mutation"
DOI: 10.1002/humu.24465
Abstract: Long‐read sequencing (LRS) has been around for more than a decade, but widespread adoption of the technology has been slow due to the perceived high error rates and high sequencing cost. This is changing due… read more here.
Keywords: diagnostics constitutional; sequencing molecular; lrs; read sequencing ... See more keywords
Dealing with Pseudogenes in Molecular Diagnostics in the Next Generation Sequencing Era.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1503-4_22
Abstract: Presence of pseudogenes is a dreadful issue in next generation sequencing (NGS), because their contamination can interfere with the detection of variants in the genuine gene and generate false positive and false negative variants.In this… read more here.
Keywords: pseudogenes molecular; dealing pseudogenes; next generation; molecular diagnostics ... See more keywords
Molecular Diagnostics of Ageing and Tackling Age-related Disease.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in pharmacological sciences"
DOI: 10.1016/j.tips.2016.11.005
Abstract: As average life expectancy increases there is a greater focus on health-span and, in particular, how to treat or prevent chronic age-associated diseases. Therapies which were able to control 'biological age' with the aim of… read more here.
Keywords: ageing tackling; age; disease; tackling age ... See more keywords
Accuracy of Commercial Molecular Diagnostics for the Detection of Pulmonary Tuberculosis in China: A Systematic Review
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-41074-8
Abstract: This systematic review assesses the accuracy of molecular diagnostic methods for the detection of pulmonary tuberculosis in studies performed in China, published in Chinese and English. We searched for studies that assessed the accuracy of… read more here.
Keywords: pulmonary tuberculosis; detection; sensitivity; molecular diagnostics ... See more keywords
Molecular Diagnostics in Pediatric Brain Tumors: Impact on Diagnosis and Clinical Decision-Making - A Selected Case Series.
Sign Up to like & getrecommendations! Published in 2018 at "Klinische Padiatrie"
DOI: 10.1055/a-0637-9653
Abstract: Central nervous system (CNS) tumors account for the highest mortality among pediatric malignancies. Accurate diagnosis is essential for optimal clinical management. The increasing use of molecular diagnostics has opened up novel possibilities for more precise… read more here.
Keywords: diagnosis; cns tumors; decision making; clinical decision ... See more keywords
CRISPR-Cas based molecular diagnostics for foodborne pathogens.
Sign Up to like & getrecommendations! Published in 2022 at "Critical reviews in food science and nutrition"
DOI: 10.1080/10408398.2022.2153792
Abstract: Foodborne pathogenic infection has brought multifaceted issues to human life, leading to an urgent demand for advanced detection technologies. CRISPR/Cas-based biosensors have the potential to address various challenges that exist in conventional assays such as… read more here.
Keywords: foodborne pathogens; molecular diagnostics; diagnostics foodborne; based molecular ... See more keywords
Molecular diagnosis of antimicrobial resistance in Escherichia coli
Sign Up to like & getrecommendations! Published in 2018 at "Expert Review of Molecular Diagnostics"
DOI: 10.1080/14737159.2018.1439381
Abstract: ABSTRACT Introduction: Antimicrobial resistance is a growing global public health threat. The complexities of antimicrobial resistance in gram-negative bacteria such as Escherichia coli pose significant diagnostic and therapeutic challenges. Molecular diagnostics are emerging in this… read more here.
Keywords: diagnosis antimicrobial; escherichia coli; antimicrobial resistance; resistance ... See more keywords
Implementation and new insights in molecular diagnostics for HIV infection
Sign Up to like & getrecommendations! Published in 2018 at "Expert Review of Molecular Diagnostics"
DOI: 10.1080/14737159.2018.1464393
Abstract: ABSTRACT Introduction: Acquired immunodeficiency syndrome (AIDS) is a kind of acquired disease that breaks down the immune system. Human immunodeficiency virus (HIV) is the causative agent of AIDS. By the end of 2016, there were… read more here.
Keywords: hiv infection; insights molecular; implementation new; new insights ... See more keywords