Suppressing Inversion of a Chiral Polycyclic Aromatic Aza Monkey Saddle by Molecular Editing
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DOI: 10.1002/hlca.202400158
Abstract: The synthesis of chiral polycyclic aromatic hydrocarbons with monkey saddle topology are a fascinating class of negatively curved compounds. To make these valuable building blocks for chirality‐assisted synthesis (CAS) approaches, the inversion barriers between the… read more here.
Keywords: polycyclic aromatic; aza monkey; monkey saddle; monkey ... See more keywords
Molecular Editing of Toluene by Sequential meta-C-H/Benzylic C-N Deaminative Functionalizations.
Sign Up to like & getrecommendations! Published in 2024 at "Organic letters"
DOI: 10.1021/acs.orglett.4c02781
Abstract: An approach to synthesizing structurally diverse toluene derivatives via sequential meta-C-H and benzylic C-N deaminative functionalization was developed by using a recyclable bifunctional directing template. The functionalized Katritzky salt intermediates are shown to be engaged… read more here.
Keywords: editing toluene; meta benzylic; sequential meta; benzylic deaminative ... See more keywords
A Formal 1,2-Stevens Rearrangement of Thioester Ylides as a Single-Atom Molecular Editing Tool.
Sign Up to like & getrecommendations! Published in 2024 at "Organic letters"
DOI: 10.1021/acs.orglett.4c04495
Abstract: A rhodium-catalyzed reaction of thioesters with diazo reagents was recognized as a powerful and unprecedented tool for single-atom molecular editing by the insertion of a single carbon atom into the C(O)─S thioester bond, thereby leading… read more here.
Keywords: formal stevens; tool; thioester; single atom ... See more keywords