Deciphering the Molecular Effects of Mutations on ATRX Cause ATRX Syndrome: A Molecular Dynamics Study
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.25984
Abstract: α‐thalassemia mental retardation X‐linked (ATRX) syndrome is caused by the dysfunction of ATRFfigX protein. The present study explored the structural consequences influenced by two observed mutations V194I and C220R on ADD domain of ATRX protein… read more here.
Keywords: deciphering molecular; molecular dynamics; atrx syndrome; add domain ... See more keywords
Molecular effects of copper on the reproductive system of mytilus galloprovincialis
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23114
Abstract: This study aims to assess the effects induced by 24 hr exposure to a subtoxic copper concentration on the reproductive system (gonads, spermatozoa, and protamine‐like [PL] proteins) of Mytilus galloprovincialis. Inductively coupled plasma–mass spectrometry indicated accumulation… read more here.
Keywords: system; mytilus galloprovincialis; exposed mussels; molecular effects ... See more keywords
Molecular Effects of Cardiac Troponin DCM Mutations on Calcium Sensitivity and Myofilament Activation - an Integrated Multi-Scale Modeling Study
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.1744
Abstract: Mutations in cTnC (D75Y, E59D and G159D), a key regulatory protein of myofilament contraction, have been associated with dilated cardiomyopathy (DCM). Despite reports of altered myofilament function in these mutants, the underlying molecular alterations caused… read more here.
Keywords: ctnc; calcium sensitivity; molecular effects; multi scale ... See more keywords
Biological actions and molecular effects of resveratrol, pterostilbene, and 3'-hydroxypterostilbene.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of food and drug analysis"
DOI: 10.1016/j.jfda.2016.07.004
Abstract: Stilbenes are a class of polyphenolic compounds, naturally found in a wide variety of dietary sources such as grapes, berries, peanuts, red wine, and some medicinal plants. There are several well-known stilbenes including trans-resveratrol, pterostilbene,… read more here.
Keywords: pterostilbene hydroxypterostilbene; actions molecular; effects resveratrol; molecular effects ... See more keywords
Behavioural and molecular effects of cannabidiolic acid in mice.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118271
Abstract: AIMS Cannabidiolic acid (CBDA) is one of the most abundant phytocannabinoid acids in the Cannabis sativa plant. It has been shown that it is able to exert some therapeutic effects such as antiemetic, anti-inflammatory, anxiolytic… read more here.
Keywords: molecular effects; behavioural molecular; mice; cannabidiolic acid ... See more keywords
Functional and molecular effects of TNF-α on human iPSC-derived cardiomyocytes
Sign Up to like & getrecommendations! Published in 2021 at "Stem cell research"
DOI: 10.1016/j.scr.2021.102218
Abstract: Proinflammatory molecule tumor necrosis factor alpha (TNF-α) is predominantly elevated in cytokine storm as well as worsening cardiac function. Here we model the molecular and functional effects of TNF-α in cardiomyocytes (CMs) derived from human… read more here.
Keywords: functional molecular; tnf treatment; treatment; molecular effects ... See more keywords
Cellular and molecular effects of yeast probiotics on cancer
Sign Up to like & getrecommendations! Published in 2017 at "Critical Reviews in Microbiology"
DOI: 10.1080/1040841x.2016.1179622
Abstract: Abstract The cancer is one of the main causes of human deaths worldwide. The exact mechanisms of initiation and progression of malignancies are not clear yet, but there is a common agreement about the role… read more here.
Keywords: effects yeast; probiotic yeasts; yeast probiotics; molecular effects ... See more keywords
Behavioral and Molecular Effects Induced by Cannabidiol and Valproate Administration in the GASH/Sal Model of Acute Audiogenic Seizures
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2020.612624
Abstract: Despite evidence that supports cannabidiol (CBD) as an anticonvulsant agent, there remains controversy over the antiseizure efficacy, possible adverse effects, and synergistic interactions with classic antiepileptics such as valproate (VPA). The genetic audiogenic seizure hamster… read more here.
Keywords: cbd; molecular effects; behavioral molecular; gash ... See more keywords
The Molecular Effects of BDNF Synthesis on Skeletal Muscle: A Mini-Review
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.934714
Abstract: The brain-derived neurotrophic factor (BDNF) is a member of the nerve growth factor family which is generated mainly by the brain. Its main role involve synaptic modulation, neurogenesis, neuron survival, immune regulation, myocardial contraction, and… read more here.
Keywords: mini review; skeletal muscle; muscle; molecular effects ... See more keywords
Cellular and Molecular Effects of Eribulin in Preclinical Models of Hematologic Neoplasms
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14246080
Abstract: Simple Summary Hematologic neoplasms comprise a heterogeneous group of diseases that interfere with normal blood production. Treating patients who fail available therapies for these diseases is an ongoing challenge. Thus, the search for new treatment… read more here.
Keywords: effects eribulin; hematologic neoplasms; cellular molecular; blood ... See more keywords
Molecular Effects of Low-Intensity Shock Wave Therapy on L6 Dorsal Root Ganglion/Spinal Cord and Blood Oxygenation Level-Dependent (BOLD) Functional Magnetic Resonance Imaging (fMRI) Changes in Capsaicin-Induced Prostatitis Rat Models
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23094716
Abstract: Neurogenic inflammation and central sensitization play a role in chronic prostatitis/chronic pelvic pain syndrome. We explore the molecular effects of low-intensity shock wave therapy (Li-ESWT) on central sensitization in a capsaicin-induced prostatitis rat model. Male… read more here.
Keywords: effects low; dorsal; spinal cord; prostatitis ... See more keywords