Predicting Drug-Induced Liver Injury Using Convolutional Neural Network and Molecular Fingerprint-Embedded Features
Sign Up to like & getrecommendations! Published in 2020 at "ACS Omega"
DOI: 10.1021/acsomega.0c03866
Abstract: As a critical issue in drug development and postmarketing safety surveillance, drug-induced liver injury (DILI) leads to failures in clinical trials as well as retractions of on-market approved drugs. Therefore, it is important to identify… read more here.
Keywords: fingerprint embedded; induced liver; molecular fingerprint; drug induced ... See more keywords
Abstract 3608: Molecular fingerprint sequencing for minimal residual disease detection in breast cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-3608
Abstract: Introduction: The substantial majority of breast cancers present with early-stage disease, although micro-metastatic disease may be established at the time of diagnosis and may ultimately result in metastatic disease recurrence. Prior studies have shown that… read more here.
Keywords: molecular fingerprint; disease; breast cancer; residual disease ... See more keywords
Compact Ho:YLF-pumped ZnGeP2-based optical parametric amplifiers tunable in the molecular fingerprint regime.
Sign Up to like & getrecommendations! Published in 2020 at "Optics letters"
DOI: 10.1364/ol.389535
Abstract: We report on a compact mid-infrared laser architecture, comprising a chain of $ {\rm ZnGeP}_2 $ZnGeP2-based optical parametric amplifiers (OPAs), which afford a higher energy yield ($ \mathbin{\lower.3ex\hbox{$\buildrel \lt \over{\smash{\scriptstyle\sim}\vphantom{_x}}$}} 60\;\unicode{x00B5} {\rm J} $∼x read more here.
Keywords: optical parametric; molecular fingerprint; parametric amplifiers; zngep2 based ... See more keywords
Modeling the molecular fingerprint of protein-lipid interactions of MLKL on complex bilayers
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2022.1088058
Abstract: Lipids, the structural part of membranes, play important roles in biological functions. However, our understanding of their implication in key cellular processes such as cell division and protein-lipid interaction is just emerging. This is the… read more here.
Keywords: lipid interactions; protein lipid; molecular fingerprint; modeling molecular ... See more keywords
Tracking the Molecular Fingerprint of Head and Neck Cancer for Recurrence Detection in Liquid Biopsies
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23052403
Abstract: The 5-year relative survival for patients with head and neck cancer, the seventh most common form of cancer worldwide, was reported as 67% in developed countries in the second decade of the new millennium. Although… read more here.
Keywords: cancer; neck cancer; molecular fingerprint; head neck ... See more keywords
Molecular Fingerprint of Human Pathological Synoviocytes in Response to Extractive Sulfated and Biofermentative Unsulfated Chondroitins
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232415865
Abstract: Pharma-grade extractive chondroitin sulfate (CS) is widely used for osteoarthritis (OA) treatment. Recently, unsulfated biofermentative chondroitin (BC) proved positive effects in OA in vitro model. This study, based on primary pathological human synoviocytes, aimed to… read more here.
Keywords: synoviocytes response; fingerprint human; molecular fingerprint; pathological synoviocytes ... See more keywords
Molecular Fingerprint Imaging to Identify Dental Caries Using Raman Spectroscopy
Sign Up to like & getrecommendations! Published in 2020 at "Materials"
DOI: 10.3390/ma13214900
Abstract: Tooth loss impairs mastication, deglutition and esthetics and affects systemic health through nutritional deficiency, weight loss, muscle weakness, delayed wound healing, and bone fragility. Approximately 90% of tooth loss is due to dental caries and… read more here.
Keywords: using raman; molecular fingerprint; dental caries; spectroscopy ... See more keywords