High-Throughput Reconstruction of Ancestral Protein Sequence, Structure, and Molecular Function.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8736-8_8
Abstract: Ancestral protein sequence reconstruction is a powerful technique for explicitly testing hypotheses about the evolution of molecular function, allowing researchers to meticulously dissect how historical changes in protein sequence impacted functional repertoire by altering the… read more here.
Keywords: reconstruction; protein sequence; structure; function ... See more keywords
Molecular Function of cGAS-STING in SARS-CoV-2: A Novel Approach to COVID-19 Treatment
Sign Up to like & getrecommendations! Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/6189254
Abstract: Coronavirus illness 2019 is a significant worldwide health danger that began with severe acute respiratory syndrome coronavirus two infections. It is the largest pandemic of our lifetime to date, affecting millions of people and crippling… read more here.
Keywords: covid; molecular function; cgas sting; function cgas ... See more keywords
Molecular Function and Contribution of TBX4 in Development and Disease.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of respiratory and critical care medicine"
DOI: 10.1164/rccm.202206-1039tr
Abstract: Over the past decade recognition of the profound impact of the T-box 4 (TBX4) gene, which encodes a member of the evolutionarily conserved family of T-box-containing transcription factors, upon respiratory diseases has emerged. The developmental… read more here.
Keywords: disease; development; molecular function; tbx4 ... See more keywords
The glycoproteomics of hawk and caiman tears
Sign Up to like & getrecommendations! Published in 2021 at "BMC Veterinary Research"
DOI: 10.1186/s12917-021-03088-1
Abstract: Background Glycoproteins are important tear components that participate in the stability of the ocular surface. However, the glycopeptides that are present in the tears of wild animals have not yet been described. This work aimed… read more here.
Keywords: tear film; caiman tears; glycoproteomics hawk; molecular function ... See more keywords
Towards refactoring the Molecular Function Ontology with a UML profile for function modeling
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biomedical Semantics"
DOI: 10.1186/s13326-017-0152-y
Abstract: BackgroundGene Ontology (GO) is the largest resource for cataloging gene products. This resource grows steadily and, naturally, this growth raises issues regarding the structure of the ontology. Moreover, modeling and refactoring large ontologies such as… read more here.
Keywords: function modeling; ontology; function; towards refactoring ... See more keywords
The Biological and Molecular Function of LINC00665 in Human Cancers
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.886034
Abstract: Long non-coding RNAs (lncRNAs) are more than 200 nucleotides in length and are implicated in the development of human cancers, without protein-coding function. Mounting evidence indicates that cancer initiation and progression are triggered by lncRNA… read more here.
Keywords: function; biological molecular; molecular function; human cancers ... See more keywords
Serial-Omics and Molecular Function Study Provide Novel Insight into Cucumber Variety Improvement
Sign Up to like & getrecommendations! Published in 2022 at "Plants"
DOI: 10.3390/plants11121609
Abstract: Cucumbers are rich in vitamins and minerals. The cucumber has recently become one of China’s main vegetable crops. More specifically, the adjustment of the Chinese agricultural industry’s structure and rapid economic development have resulted in… read more here.
Keywords: serial omics; omics molecular; cucumber; molecular function ... See more keywords