Barrett's esophagus: The pathomorphological and molecular genetic keystones of neoplastic progression
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Medicine"
DOI: 10.1002/cam4.4447
Abstract: Barrett's esophagus is a widespread chronically progressing disease of heterogeneous nature. A life threatening complication of this condition is neoplastic transformation, which is often overlooked due to lack of standardized approaches in diagnosis, preventative measures… read more here.
Keywords: barrett; neoplastic progression; barrett esophagus; esophagus pathomorphological ... See more keywords
Molecular genetic positioning of small intestine and papilla of Vater carcinomas including clinicopathological classification.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.5877
Abstract: Small intestine carcinoma (SIC) cases in Japan have recently been treated with chemotherapy according to colorectal carcinoma classification, while papilla of Vater carcinoma (PVC) cases according to cholangiocarcinoma (CHC) classification. However, few research reports support… read more here.
Keywords: classification; small intestine; papilla vater; molecular genetic ... See more keywords
Molecular and quantitative genetic variation within and between populations of the declining grassland species Saxifraga granulata
Sign Up to like & getrecommendations! Published in 2022 at "Ecology and Evolution"
DOI: 10.1002/ece3.9462
Abstract: Abstract Formerly common plant species are expected to be particularly susceptible to recent habitat fragmentation. We studied the population genetics of 19 recently fragmented Saxifraga granulata populations (max. distance 61 km) in Luxembourg and neighboring Germany… read more here.
Keywords: genetic variation; molecular genetic; quantitative genetic; differentiation ... See more keywords
Clinical and molecular genetic analysis of a Chinese family with hereditary elliptocytosis caused by a novel mutation in the EPB41 gene
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.23781
Abstract: Hereditary elliptocytosis (HE) is a heterogeneous red blood cell membrane disorder characterized by the presence of elliptocytes on a peripheral blood smear. Clinical manifestations of HE vary widely from asymptomatic carriers to patients with severe… read more here.
Keywords: clinical molecular; hereditary elliptocytosis; elliptocytosis; molecular genetic ... See more keywords
Molecular Genetic Techniques for the Proteoglycan Functions in Drosophila.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1398-6_32
Abstract: Several classes of heparan sulfate proteoglycan (HSPG) core proteins and all HS biosynthetic/modifying enzymes are evolutionarily conserved from human to Drosophila melanogaster. This genetically tractable model offers highly sophisticated techniques to manipulate gene function in… read more here.
Keywords: molecular genetic; genetic techniques; biology; techniques proteoglycan ... See more keywords
Molecular Genetic Characterization of Mutagenesis Using a Highly Sensitive Single-Stranded DNA Reporter System in Budding Yeast.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7306-4_4
Abstract: Mutations are permanent alterations to the coding content of DNA. They are starting material for the Darwinian evolution of species by natural selection, which has yielded an amazing diversity of life on Earth. Mutations can… read more here.
Keywords: dna; reporter system; molecular genetic; highly sensitive ... See more keywords
The molecular genetic basis of creativity: a mini review and perspectives.
Sign Up to like & getrecommendations! Published in 2022 at "Psychological research"
DOI: 10.1007/s00426-022-01649-z
Abstract: Although creativity is one of the defining features of human species, it is just the beginning of an ambitious attempt for psychologists to understand its genetic basis. With ongoing efforts, great progress has been achieved… read more here.
Keywords: creativity mini; genetic basis; molecular genetic; mini review ... See more keywords
Molecular genetic and immunotherapeutic targets in metastatic melanoma
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DOI: 10.1007/s00428-017-2113-3
Abstract: In recent years, melanoma treatment has radically changed with the emergence of targeted therapies and immunotherapies. Both have led to improved survival for patients with advanced or unresectable melanoma. Targeted therapies with BRAF inhibitors in… read more here.
Keywords: genetic immunotherapeutic; treatment; molecular genetic; metastatic melanoma ... See more keywords
RNAseq Supports the Molecular Genetic Diagnosis of Late-Onset ADA Deficiency
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Immunology"
DOI: 10.1007/s10875-019-00625-4
Abstract: To the Editor: Adenosine deaminase (ADA) deficiency is an autosomal recessive disorder of purine metabolism that typically presents as a severe combined immunodeficiency in infancy (OMIM: 102700). Approximately 10–15% of patients have a delayed clinical… read more here.
Keywords: ada deficiency; molecular genetic; immunology; diagnosis ... See more keywords
Exaptation at the molecular genetic level
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DOI: 10.1007/s11427-018-9447-8
Abstract: The realization that body parts of animals and plants can be recruited or coopted for novel functions dates back to, or even predates the observations of Darwin. S.J. Gould and E.S. Vrba recognized a mode… read more here.
Keywords: exaptation molecular; biology; genetic level; molecular genetic ... See more keywords
Molecular genetic testing strategies used in diagnostic flow for hereditary endocrine tumour syndromes
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DOI: 10.1007/s12020-021-02636-x
Abstract: Although current guidelines prefer the use of targeted testing or small-scale gene panels for identification of genetic susceptibility of hereditary endocrine tumour syndromes, next generation sequencing based strategies have been widely introduced into every day… read more here.
Keywords: genetic testing; hereditary endocrine; endocrine tumour; tumour syndromes ... See more keywords