Molecular insight into the early stage of amyloid-β(1-42) Homodimers aggregation influenced by histidine tautomerism.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.06.078
Abstract: Aggregated amyloid β-peptide (Aβ) in small oligomeric forms inside the brain causes synaptic function disruption and the development of Alzheimer's disease (AD). Histidine is an important amino acid that may lead to structural changes. Aβ42… read more here.
Keywords: aggregation; histidine; molecular insight; insight early ... See more keywords
Molecular insight into the oil extraction and transport in CO2 flooding with reservoir depressurization
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Heat and Mass Transfer"
DOI: 10.1016/j.ijheatmasstransfer.2019.119051
Abstract: Abstract In this study, the mechanism of CO2 extracting hydrocarbon with reservoir depressurization was investigated through molecular dynamic simulations. First, the effects of different depressurization rates (ΔP/0.1, 0.5, 1.0 and 2.0 ns) on the extraction results… read more here.
Keywords: extraction; depressurization; molecular insight; reservoir depressurization ... See more keywords
Molecular insight into binding affinities and blockade effects of selected flavonoid compounds on the PD-1/PD-L1 pathway
Sign Up to like & getrecommendations! Published in 2024 at "RSC Advances"
DOI: 10.1039/d4ra03877k
Abstract: This study investigated the binding mechanisms of the flavonoids apigenin (Api), kaempferol (Kmp), and quercetin (Que) to the PD-L1 dimer using a combination of molecular modeling and experimental techniques. The binding free energy results demonstrated… read more here.
Keywords: insight binding; flavonoids could; molecular insight; affinities blockade ... See more keywords
A Molecular Insight into the Role of Antioxidants in Nonalcoholic Fatty Liver Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/9233650
Abstract: Nonalcoholic fatty liver disease (NAFLD) defines fat accumulation in the liver, and it is commonly associated with metabolic syndromes like diabetes and obesity. Progressive NAFLD leads to nonalcoholic steatohepatitis (NASH) and ultimately causes cirrhosis and… read more here.
Keywords: nonalcoholic fatty; fatty liver; molecular insight; nafld ... See more keywords
Molecular insight into how γ-TuRC makes microtubules.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cell science"
DOI: 10.1242/jcs.245464
Abstract: As one of four filament types, microtubules are a core component of the cytoskeleton and are essential for cell function. Yet how microtubules are nucleated from their building blocks, the αβ-tubulin heterodimer, has remained a… read more here.
Keywords: insight turc; molecular insight; turc; makes microtubules ... See more keywords
A molecular insight into the lipid changes of pig Longissimus thoracis muscle following dietary supplementation with functional ingredients
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0264953
Abstract: In this work, the Longissimus thoracis pig skeletal muscle was used as a model to investigate the impact of two different diets, supplemented with n-3 polyunsaturated fatty acids from extruded linseed (L) and polyphenols from… read more here.
Keywords: lipid changes; muscle; changes pig; molecular insight ... See more keywords
Molecular insight into Aspergillus oryzae β-mannanase interacting with mannotriose revealed by molecular dynamic simulation study
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0268333
Abstract: Fungal β-mannanases hydrolyze β-1, 4-glycosidic bonds of mannans and find application in the generation of mannose and prebiotic mannooligosaccharides (MOS). Previously, a MOS generating β-mannanase from Aspergillus oryzae MTCC 1846 (βManAo) was characterized and its… read more here.
Keywords: mannanase; oryzae mannanase; molecular insight; insight aspergillus ... See more keywords
Physiological and molecular insight of microbial biostimulants for sustainable agriculture
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2023.1041413
Abstract: Increased food production to cater the need of growing population is one of the major global challenges. Currently, agro-productivity is under threat due to shrinking arable land, increased anthropogenic activities and changes in the climate… read more here.
Keywords: biostimulants plants; molecular insight; microbial biostimulants; insight microbial ... See more keywords
Adult Gliomas: From Molecular Insight to Clinical Horizons
Sign Up to like & getrecommendations! Published in 2025 at "Current Oncology"
DOI: 10.3390/curroncol32120659
Abstract: Over the past decade, the management of adult gliomas has been reshaped by profound scientific and clinical advances [...]. read more here.
Keywords: oncology; gliomas molecular; clinical horizons; adult gliomas ... See more keywords
Molecular Insight of Plants Response to Drought Stress: Perspectives and New Insights towards Food Security
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms25094988
Abstract: In the face of climate-induced challenges, understanding the intricate molecular mechanisms underlying drought tolerance in plants has become imperative [...]. read more here.
Keywords: plants response; drought stress; molecular insight; stress perspectives ... See more keywords
Molecular insight into the potential functional role of pseudoenzyme GFOD1 via interaction with NKIRAS2
Sign Up to like & getrecommendations! Published in 2024 at "Acta Biochimica et Biophysica Sinica"
DOI: 10.3724/abbs.2024105
Abstract: The glucose-fructose oxidoreductase/inositol dehydrogenase/rhizopine catabolism protein (Gfo/Idh/MocA) family includes a variety of oxidoreductases with a wide range of substrates that utilize NAD or NADP as redox cofactor. Human contains two members of this family, namely… read more here.
Keywords: pseudoenzyme; molecular insight; functional role; gfod1 ... See more keywords