Benzocoumarin‐Fused Triskelions Exhibit AIEE due to Inhibited Molecular Inversion
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.202400015
Abstract: Developing aggregation‐induced emission luminogens (AIEgens) is a unique strategy for alleviating concentration quenching of π‐conjugated organic compounds. This AIE behaviour can be induced not only in organic dyes with rotors but also in invertible π‐conjugated… read more here.
Keywords: triskelions exhibit; benzocoumarin fused; exhibit aiee; molecular inversion ... See more keywords
Using single molecule Molecular Inversion Probes as a cost‐effective, high‐throughput sequencing approach to target all genes and loci associated with macular diseases
Sign Up to like & getrecommendations! Published in 2022 at "Human Mutation"
DOI: 10.1002/humu.24489
Abstract: Macular degenerations (MDs) are a subgroup of retinal disorders characterized by central vision loss. Knowledge is still lacking on the extent of genetic and nongenetic factors influencing inherited MD (iMD) and age‐related MD (AMD) expression.… read more here.
Keywords: single molecule; cost effective; molecule molecular; high throughput ... See more keywords
High-throughput genotyping of Plasmodium vivax in the Peruvian Amazon via molecular inversion probes
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-54731-y
Abstract: Plasmodium vivax transmission occurs throughout the tropics and is an emerging threat in areas of Plasmodium falciparum decline, causing relapse infections that complicate treatment and control. Targeted sequencing for P. falciparum has been widely deployed… read more here.
Keywords: plasmodium; peruvian amazon; molecular inversion; vivax ... See more keywords
Profiling of the metabolic transcriptome via single molecule molecular inversion probes
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-11035-0
Abstract: Cancer-specific metabolic alterations are of high interest as therapeutic targets. These alterations vary between tumor types, and to employ metabolic targeting to its fullest potential there is a need for robust methods that identify candidate… read more here.
Keywords: molecule molecular; molecular inversion; inversion probes; single molecule ... See more keywords
BRCA Testing by Single-Molecule Molecular Inversion Probes.
Sign Up to like & getrecommendations! Published in 2017 at "Clinical chemistry"
DOI: 10.1373/clinchem.2016.263897
Abstract: BACKGROUND Despite advances in next generation DNA sequencing (NGS), NGS-based single gene tests for diagnostic purposes require improvements in terms of completeness, quality, speed, and cost. Single-molecule molecular inversion probes (smMIPs) are a technology with… read more here.
Keywords: molecule; molecular inversion; single molecule; inversion probes ... See more keywords
Ultrasensitive Detection of Chimerism by Single-Molecule Molecular Inversion Probe Capture and High-Throughput Sequencing of Copy Number Deletion Polymorphisms.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical chemistry"
DOI: 10.1373/clinchem.2017.284737
Abstract: BACKGROUND Genomic chimerism, the co-occurrence of cells from different genetic origins, provides important diagnostic information in diverse clinical contexts, including graft injury detection and longitudinal surveillance of hematopoietic stem cell transplantation patients, but existing assays… read more here.
Keywords: molecular inversion; detection; single molecule; chimerism ... See more keywords