Molecular investigations into the unfoldase action of severing enzymes on microtubules
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DOI: 10.1002/cm.21606
Abstract: Microtubule (MT)‐associated proteins regulate the dynamic behavior of MTs during cellular processes. MT severing enzymes are the associated proteins which destabilize MTs by removing subunits from the lattice. One model for how severing enzymes remove… read more here.
Keywords: enzymes microtubules; action severing; severing enzymes; unfoldase action ... See more keywords
Molecular investigations on Candida glabrata clinical isolates for pharmacological targeting
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DOI: 10.1039/d2ra02092k
Abstract: Prevalence of drug resistant C. glabrata strains in hospitalized immune-compromised patients with invasive fungal infections has increased at an unexpected pace. This has greatly pushed researchers in identification of mutations/variations in clinical isolates for better… read more here.
Keywords: clinical isolates; candida glabrata; investigations candida; molecular investigations ... See more keywords
Next-Generation Molecular Investigations in Lysosomal Diseases: Clinical Integration of a Comprehensive Targeted Panel
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DOI: 10.3390/diagnostics11020294
Abstract: Diagnosis of lysosomal disorders (LDs) may be hampered by their clinical heterogeneity, phenotypic overlap, and variable age at onset. Conventional biological diagnostic procedures are based on a series of sequential investigations and require multiple sampling.… read more here.
Keywords: investigations lysosomal; generation molecular; panel; molecular investigations ... See more keywords
Molecular Investigations of Protein Aggregation in the Pathogenesis of Amyotrophic Lateral Sclerosis
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DOI: 10.3390/ijms24010704
Abstract: Amyotrophic lateral sclerosis (ALS) is a devastating progressive neurodegenerative disorder characterized by selective loss of lower and upper motor neurons (MNs) in the brain and spinal cord, resulting in paralysis and eventually death due to… read more here.
Keywords: lateral sclerosis; investigations protein; protein aggregation; molecular investigations ... See more keywords