LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "molecular landscape" as a keyword



SA74 GENETIC UNDERPINNINGS OF SOCIAL WITHDRAWAL IN THE GENERAL POPULATION

Sign Up to like & get
recommendations! Published in 2019 at "European Neuropsychopharmacology"

DOI: 10.1016/j.euroneuro.2017.08.146

Abstract: Background Social withdrawal is present as a trait in the general population and is a common early symptom of neuropsychiatric conditions such as Alzheimer's Disease (AD), Schizophrenia (SCZ) and Major Depressive Disorder (MDD). However, the… read more here.

Keywords: general population; withdrawal general; molecular landscape; withdrawal ... See more keywords

The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions

Sign Up to like & get
recommendations! Published in 2018 at "Nature Medicine"

DOI: 10.1038/nm.4439

Abstract: We present the molecular landscape of pediatric acute myeloid leukemia (AML) and characterize nearly 1,000 participants in Children's Oncology Group (COG) AML trials. The COG–National Cancer Institute (NCI) TARGET AML initiative assessed cases by whole-genome,… read more here.

Keywords: myeloid leukemia; molecular landscape; acute myeloid; pediatric acute ... See more keywords

Molecular landscape of long noncoding RNAs in brain disorders

Sign Up to like & get
recommendations! Published in 2020 at "Molecular Psychiatry"

DOI: 10.1038/s41380-020-00947-5

Abstract: According to current paradigms, various risk factors, such as genetic mutations, oxidative stress, neural network dysfunction, and abnormal protein degradation, contribute to the progression of brain disorders. Through the cooperation of gene transcripts in biological… read more here.

Keywords: long noncoding; brain disorders; molecular landscape; noncoding rnas ... See more keywords

The clinicopathological and molecular landscape of breast cancer patients: a retrospective study in Sulaimaniyah, Iraq

Sign Up to like & get
recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-12896-6

Abstract: Breast cancer (BC) is the most common cancer among females and the second leading cause of cancer-related death in women, with different management modalities. To determine the premenopausal BC patients’ clinicopathological and molecular landscape. This… read more here.

Keywords: cancer; breast cancer; breast; clinicopathological molecular ... See more keywords
Photo from archive.org

Molecular landscape of thymic epithelial tumors.

Sign Up to like & get
recommendations! Published in 2021 at "Seminars in diagnostic pathology"

DOI: 10.1053/j.semdp.2021.06.011

Abstract: Thymic epithelial tumors (TETs) are extremely rare and represent the most frequent tumors of the anterior mediastinum originating from epithelial cells in the thymus. Thymic epithelial tumors include thymomas (TM), thymic carcinomas (TC) and thymic… read more here.

Keywords: pathology; landscape thymic; molecular landscape; thymic epithelial ... See more keywords

Elucidating the molecular landscape of the stratum corneum

Sign Up to like & get
recommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2114380119

Abstract: Significance Skin is recognized as an intricate assembly of molecular components, which facilitate cell signaling, metabolism, and protein synthesis mechanisms in order to offer protection, regulation, and sensation to the body. Our study takes significant… read more here.

Keywords: stratum corneum; elucidating molecular; molecular landscape; landscape stratum ... See more keywords

How to treat histone 3 altered gliomas: molecular landscape and therapeutic developments

Sign Up to like & get
recommendations! Published in 2022 at "Expert Review of Clinical Pharmacology"

DOI: 10.1080/17512433.2023.2163385

Abstract: ABSTRACT Introduction Diffuse midline gliomas (DMG) and diffuse hemispheric glioma (DHG) are both rare tumors characterized and recognized for specific alterations of histone 3 including H3K27 (DMG) and H3G34 (DHG). Despite these tumors arising from… read more here.

Keywords: treat histone; histone altered; molecular landscape; altered gliomas ... See more keywords

Cross-platform analysis reveals cellular and molecular landscape of glioblastoma invasion.

Sign Up to like & get
recommendations! Published in 2022 at "Neuro-oncology"

DOI: 10.1093/neuonc/noac186

Abstract: BACKGROUND Improved treatment of glioblastoma (GBM) needs to address tumor invasion, a hallmark of the disease that remains poorly understood. In this study, we profiled GBM invasion through integrative analysis of histological and single-cell RNA… read more here.

Keywords: molecular landscape; analysis; invasion; cellular molecular ... See more keywords

The clinical and molecular landscape of diffuse hemispheric glioma, H3 G34-mutant

Sign Up to like & get
recommendations! Published in 2025 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaf015

Abstract: Abstract Background Diffuse hemispheric glioma, histone 3 (H3) G34-mutant, has been newly defined in the 2021 World Health Organization (WHO) classification of central nervous system tumors. Here we sought to define the prognostic roles of… read more here.

Keywords: hemispheric glioma; molecular landscape; diffuse hemispheric; g34 mutant ... See more keywords

EPCO-28. THE MOLECULAR LANDSCAPE AND ITS PROGNOSTIC IMPLICATIONS IN ADULT PAPILLARY TUMORS OF THE PINEAL REGION - A MULTICENTER YOUNGNOA INVESTIGATION

Sign Up to like & get
recommendations! Published in 2025 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaf201.0028

Abstract: Papillary tumors of the pineal region (PTPR) are rare central nervous system (CNS) neoplasms with variable clinical behavior, where robust prognostic biomarkers for adult patients remain elusive. Here, we performed comprehensive DNA methylation and copy… read more here.

Keywords: ptpr; tumors pineal; papillary tumors; pineal region ... See more keywords

Integrated clinical and molecular landscape of disseminated pediatric low-grade glioma.

Sign Up to like & get
recommendations! Published in 2025 at "Neuro-oncology"

DOI: 10.1093/neuonc/noaf245

Abstract: BACKGROUND Pediatric-type low-grade gliomas (PLGG) are the most common central nervous system (CNS) tumor in children. Many are indolent and have excellent outcomes, however some inexplicably spread throughout the CNS leading to increased morbidity and… read more here.

Keywords: integrated clinical; clinical molecular; landscape disseminated; molecular landscape ... See more keywords