Molecular Mediators and Regulators of Retinal Angiogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Seminars in Ophthalmology"
DOI: 10.1080/08820538.2022.2152706
Abstract: ABSTRACT Background Retinal neovascularization is the major cause of vision loss that affects both adults and young children including premature babies. It has been a major pathology in several retinal diseases like age-related macular degeneration… read more here.
Keywords: retinal diseases; pathology; retinal neovascularization; angiogenesis ... See more keywords
Targeting Molecular Mediators of Ferroptosis and Oxidative Stress for Neurological Disorders
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/3999083
Abstract: With the acceleration of population aging, nervous system diseases including Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), anxiety, depression, stroke, and traumatic brain injury (TBI) have become a huge burden on families and… read more here.
Keywords: stress; neurological disorders; oxidative stress; ferroptosis oxidative ... See more keywords
Systematic identification of molecular mediators of interspecies sensing in a community of two frequently coinfecting bacterial pathogens
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DOI: 10.1371/journal.pbio.3001679
Abstract: Bacteria typically exist in dynamic, multispecies communities where polymicrobial interactions influence fitness. Elucidating the molecular mechanisms underlying these interactions is critical for understanding and modulating bacterial behavior in natural environments. While bacterial responses to foreign… read more here.
Keywords: community; systematic identification; identification molecular; mediators interspecies ... See more keywords
Platelet-monocyte aggregates: molecular mediators of thromboinflammation
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2023.960398
Abstract: Platelets, key facilitators of primary hemostasis and thrombosis, have emerged as crucial cellular mediators of innate immunity and inflammation. Exemplified by their ability to alter the phenotype and function of monocytes, activated platelets bind to… read more here.
Keywords: platelet monocyte; aggregates molecular; monocyte aggregates; platelet ... See more keywords
Stress as a Risk Factor for Substance Use Disorders: A Mini-Review of Molecular Mediators
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2018.00309
Abstract: The extant literature supports the role of stress in enhancing the susceptibility of drug abuse progressing to a substance use disorder diagnosis. However, the molecular mediators by which stress enhances the progression from cocaine abuse… read more here.
Keywords: mini review; use; substance use; molecular mediators ... See more keywords
Lysophosphatidic Acid and Ion Channels as Molecular Mediators of Pain
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2018.00462
Abstract: Lysophosphatidic acid or LPA is a phospholipid which has been extensively linked to the generation and maintenance of pain. Several ion channels have also been shown to participate in this pathological process but the link… read more here.
Keywords: lysophosphatidic acid; ion channels; molecular mediators; ion ... See more keywords
Flux-Independent NMDAR Signaling: Molecular Mediators, Cellular Functions, and Complexities
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DOI: 10.3390/ijms19123800
Abstract: The glutamate (Glu) N-methyl-d-aspartate (NMDA) receptor (NMDAR) plays a critical role in synaptic communication given mainly by its ionotropic function that permeates Ca2+. This in turn activates calmodulin that triggers CaMKII, MAPK, CREB, and PI3K… read more here.
Keywords: signaling molecular; independent nmdar; nmdar; flux independent ... See more keywords
Cellular and Molecular Mediators of Neuroinflammation in Alzheimer Disease
Sign Up to like & getrecommendations! Published in 2019 at "International Neurourology Journal"
DOI: 10.5213/inj.1938184.092
Abstract: Alzheimer disease (AD) is a neurodegenerative disorder characterized by the loss of neuronal cells and the progressive decline of cognitive function. The major pathological culprit of AD is aggregation of amyloid-β (Aβ) and hyperphosphorylation of… read more here.
Keywords: mediators neuroinflammation; neuroinflammation alzheimer; alzheimer disease; molecular mediators ... See more keywords