Can molecular mimicry explain the cytokine storm of SARS‐CoV‐2?: An in silico approach
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27040
Abstract: PARP14 and PARP9 play a key role in macrophage immune regulation. SARS‐CoV‐2 is an emerging viral disease that triggers hyper‐inflammation known as a cytokine storm. In this study, using in silico tools, we hypothesize about… read more here.
Keywords: sars cov; molecular mimicry; parp14 parp9; cytokine storm ... See more keywords
Friends in Low Places: Intestinal Commensals Limit Colitis through Molecular Mimicry
Sign Up to like & getrecommendations! Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.09.053
Abstract: Inflammatory bowel disease is thought to arise from inappropriate inflammation to gut bacteria, yet mechanisms preventing these responses remain elusive. In this issue of Cell, Nanjundappa et al. report that Bacteroides share an epitope with a… read more here.
Keywords: low places; friends low; intestinal commensals; molecular mimicry ... See more keywords
COVID-19 and molecular mimicry: The Columbus’ egg?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2020.05.015
Abstract: Highlights • Recently, this Journal published a report about Guillain-Barré syndrome associated with COVID-19 infection.• Guillain-Barré syndrome can be due to molecular mimicry phenomena.• Molecular mimicry had already been described in another SARS.• It could… read more here.
Keywords: columbus egg; molecular mimicry; covid molecular; mimicry ... See more keywords
Molecular mimicry as a mechanism of viral immune evasion and autoimmunity
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-53658-8
Abstract: Mimicry of host protein structures, or ‘molecular mimicry’, is a common mechanism employed by viruses to evade the host’s immune system. Short linear amino acid (AA) molecular mimics can elicit cross-reactive antibodies and T cells… read more here.
Keywords: molecular mimicry; host; autoimmunity; mimicry ... See more keywords
The interplay between viral molecular mimicry and host chromatin dynamics
Sign Up to like & getrecommendations! Published in 2023 at "Nucleus"
DOI: 10.1080/19491034.2023.2216560
Abstract: ABSTRACT Molecular mimicry is a commonly used mechanism by viruses to manipulate host cellular machinery and coordinate their life cycles. While histone mimicry is well studied, viruses also employ other mimicry strategies to affect chromatin… read more here.
Keywords: mimicry; viral molecular; chromatin dynamics; host ... See more keywords
DOP027 Caudovirales may trigger molecular mimicry mechanisms in Crohn’s Disease
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjae190.0066
Abstract: Inflammatory Bowel Disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), has been increasingly associated with imbalances in the gut microbiota. Dysregulation within the gut virome has been linked to CD pathogenesis, with elevated… read more here.
Keywords: molecular mimicry; disease; proteus virus; virus isfahan ... See more keywords
Molecular Mimicry of Transposable Elements in Plants
Sign Up to like & getrecommendations! Published in 2024 at "Plant and Cell Physiology"
DOI: 10.1093/pcp/pcae058
Abstract: Abstract Transposable elements (TEs) are mobile DNA elements that are particularly abundant in the plant genomes. They have long been considered as junk DNA; however, a growing body of evidence suggests that TE insertions promote… read more here.
Keywords: molecular mimicry; plant; host; elements plants ... See more keywords
Scientific evaluation of alleged findings in HPV vaccines: Molecular mimicry and mouse models of vaccine‐induced disease
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Science"
DOI: 10.1111/cas.15482
Abstract: Cervical cancer is caused by infections of the human papillomavirus (HPV), which can be prevented by vaccinations. In Japan, although about 3000 people die of cervical cancer annually, the HPV vaccination rate has remained extremely… read more here.
Keywords: hpv vaccination; molecular mimicry; hpv; hpv vaccines ... See more keywords
The Role of Epstein–Barr Virus Molecular Mimicry in Various Autoimmune Diseases
Sign Up to like & getrecommendations! Published in 2025 at "Scandinavian Journal of Immunology"
DOI: 10.1111/sji.70016
Abstract: Rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and multiple sclerosis (MS) are complex autoimmune inflammatory diseases influenced by genetic, environmental and infectious agents like Epstein–Barr virus (EBV). EBV has been proposed to impact immune pathways… read more here.
Keywords: molecular mimicry; epstein barr; role epstein; autoimmune diseases ... See more keywords
Molecular Mimicry: a Paradigm of Host-Microbe Coevolution Illustrated by Legionella
Sign Up to like & getrecommendations! Published in 2020 at "mBio"
DOI: 10.1128/mbio.01201-20
Abstract: Through coevolution with host cells, microorganisms have acquired mechanisms to avoid the detection by the host surveillance system and to use the cell’s supplies to establish themselves. Indeed, certain pathogens have evolved proteins that imitate… read more here.
Keywords: like proteins; coevolution; eukaryotic like; host ... See more keywords
How the gut inflames the joints
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-212942
Abstract: A study by Pianta et al published in the Journal of Clinical Investigation provides new evidence that the pathogenesis of rheumatoid arthritis (RA) may involve molecular mimicry, one of the most venerable models for the… read more here.
Keywords: inflames joints; molecular mimicry; infection; gut inflames ... See more keywords