Retinoic acid regulates avian lung branching through a molecular network
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-017-2600-3
Abstract: Retinoic acid (RA) is of major importance during vertebrate embryonic development and its levels need to be strictly regulated otherwise congenital malformations will develop. Through the action of specific nuclear receptors, named RAR/RXR, RA regulates… read more here.
Keywords: avian lung; molecular network; lung branching; expression ... See more keywords
Alginate Trisaccharide Binding Sites on the Surface of β-Lactoglobulin Identified by NMR Spectroscopy: Implications for Molecular Network Formation
Sign Up to like & getrecommendations! Published in 2019 at "ACS Omega"
DOI: 10.1021/acsomega.8b03532
Abstract: β-lactoglobulin (BLG) is a promiscuous protein in terms of ligand interactions, having several binding sites reported for hydrophobic biomolecules such as fatty acids, lipids, and vitamins as well as detergents. BLG also interacts with neutral… read more here.
Keywords: binding sites; formation; molecular network; spectroscopy ... See more keywords
Selection of diverse polymorphic structures from a small dynamic molecular network controlled by the environment
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc03909e
Abstract: The complex interplay between systems and their environment plays an important role in processes ranging from self-assembly to evolution. Polymorphism, where, from the same ingredients different products can be formed, is likely to be an… read more here.
Keywords: dynamic molecular; environment; selection diverse; molecular network ... See more keywords
Mapping Conformational Changes in a Self-Assembled Two-Dimensional Molecular Network by Statistical Analysis of Conductance Images
Sign Up to like & getrecommendations! Published in 2019 at "Physical Review Applied"
DOI: 10.1103/physrevapplied.11.034070
Abstract: A self-assembled two-dimensional (2D) film of tetra-phenyl-porphyrin-4-ferrocene molecules on Au(111) is studied by STM for the presence of intra- and intermolecular correlations in the configurations of the four-pendant ferrocenyl moieties. A statistical analysis of STS… read more here.
Keywords: molecular network; assembled two; self assembled; conformational changes ... See more keywords
CERENKOV3: Clustering and molecular network-derived features improve computational prediction of functional noncoding SNPs
Sign Up to like & getrecommendations! Published in 2020 at "Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing"
DOI: 10.1142/9789811215636_0047
Abstract: Identification of causal noncoding single nucleotide polymorphisms (SNPs) is important for maximizing the knowledge dividend from human genome-wide association studies (GWAS). Recently, diverse machine learning-based methods have been used for functional SNP identification; however, this… read more here.
Keywords: molecular network; network; snps; derived features ... See more keywords
Study on Secondary Metabolites of Endophytic Fungus, Aspergillus fumigatus, from Crocus sativus L. Guided byUHPLC-HRMS/MS-Based Molecular Network
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Analytical Chemistry"
DOI: 10.1155/2022/7067665
Abstract: As a traditional Chinese medicine, Crocus sativus Linn has been used for a long time in China. However, the studies on secondary metabolites of its endophytic fungi were not fully sufficient. Thus, the endophytic fungus,… read more here.
Keywords: metabolites endophytic; crocus sativus; secondary metabolites; molecular network ... See more keywords
Using molecular network analysis to explore the characteristics of HIV-1 transmission in a China-Myanmar border area
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0268143
Abstract: Background The China-Myanmar border area is considered a hot spot of active HIV-1 recombination in Southeast Asia. To better understand the characteristics of HIV-1 transmission in this area, a cross-sectional HIV-1 molecular epidemiological survey was… read more here.
Keywords: molecular network; area; characteristics hiv; transmission ... See more keywords
Prediction of Drug–Target Interactions From Multi-Molecular Network Based on Deep Walk Embedding Model
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.00338
Abstract: Predicting drug–target interactions (DTIs) is crucial in innovative drug discovery, drug repositioning and other fields. However, there are many shortcomings for predicting DTIs using traditional biological experimental methods, such as the high-cost, time-consumption, low efficiency,… read more here.
Keywords: deep walk; network; molecular network; multi molecular ... See more keywords
Priority Intervention Targets Identified Using an In-Depth Sampling HIV Molecular Network in a Non-Subtype B Epidemics Area
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2021.642903
Abstract: Molecular network analysis based on the genetic similarity of HIV-1 is increasingly used to guide targeted interventions. Nevertheless, there is a lack of experience regarding molecular network inferences and targeted interventions in combination with epidemiological… read more here.
Keywords: intervention; molecular network; priority; hiv ... See more keywords
The relationship between protein modified folding molecular network and Alzheimer’s disease pathogenesis based on BAG2-HSC70-STUB1-MAPT expression patterns analysis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2023.1090400
Abstract: Background Alzheimer’s disease (AD) is the most common cause of dementia and cognitive decline, while its pathological mechanism remains unclear. Tauopathies is one of the most widely accepted hypotheses. In this study, the molecular network… read more here.
Keywords: network; relationship; alzheimer disease; expression ... See more keywords
Molecular Network of Colorectal Cancer and Current Therapeutic Options
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.852927
Abstract: Colorectal cancer (CRC), a leading cause of cancer-related mortalities globally, results from the accumulation of multiple genetic and epigenetic alterations in the normal colonic and rectum epithelium, leading to the progression from colorectal adenomas to… read more here.
Keywords: molecular network; cancer current; cancer; network colorectal ... See more keywords