Molecular noise can minimize the collective sensitivity of a clonal heterogeneous cell population.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of theoretical biology"
DOI: 10.1016/j.jtbi.2016.12.023
Abstract: It is now widely accepted that molecular noise, rather than be always detrimental, introduces in many circumstances the required boost to reach fundamental cellular activities or strategies otherwise unattainable. In threshold-like genetic systems, molecular noise… read more here.
Keywords: noise minimize; molecular noise; cell population; noise ... See more keywords
Molecular noise of innate immunity shapes bacteria-phage ecologies
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1007168
Abstract: Mathematical models have been used successfully at diverse scales of biological organization, ranging from ecology and population dynamics to stochastic reaction events occurring between individual molecules in single cells. Generally, many biological processes unfold across… read more here.
Keywords: innate; immunity; molecular noise; innate immunity ... See more keywords