Mantle cell lymphoma in 2022 - A comprehensive update on molecular pathogenesis, risk stratification, clinical approach, and current and novel treatments.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of hematology"
DOI: 10.1002/ajh.26523
Abstract: The field of mantle cell lymphoma (MCL) has witnessed remarkable progress due to relentless advances in molecular pathogenesis, prognostication, and newer treatments. MCL consists of a spectrum of clinical subtypes. Rarely, atypical cyclin D1-negative MCL… read more here.
Keywords: cell lymphoma; mcl; molecular pathogenesis; mantle cell ... See more keywords
Pathology and Molecular Pathogenesis of DLBCL and Related Entities
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DOI: 10.1007/978-3-030-00362-3_2
Abstract: Diffuse large B-cell lymphomas (DLBCLs) comprise a diverse group of aggressive lymphoid tumors characterized by distinct genetic, phenotypic, and clinical features, with over ten entities recognized in the updated WHO classification of hematopoietic and lymphoid… read more here.
Keywords: dlbcl; molecular pathogenesis; pathology molecular; pathology ... See more keywords
Molecular pathogenesis of leukemia and leukemic stem cells (LSCs)
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Hematology"
DOI: 10.1007/s12185-018-2550-z
Abstract: The 79th Annual Meeting of the Japanese Society of Hematology (JSH) was held over a 3-day period from Friday, October 20 to Sunday, October 22, 2017. This meeting was the first time in 18 years… read more here.
Keywords: transcription; hematology; pathogenesis leukemia; molecular pathogenesis ... See more keywords
The molecular pathogenesis of the NUP98-HOXA9 fusion protein in acute myeloid leukemia
Sign Up to like & getrecommendations! Published in 2017 at "Leukemia"
DOI: 10.1038/leu.2017.194
Abstract: diagnosis, time from diagnosis to transplant and disease status at transplant. VRD has become the most common pretransplant induction regimen after 2010. Only, half of patients are placed on post-transplant treatment at day 100 after… read more here.
Keywords: leukemia molecular; pathogenesis nup98; molecular pathogenesis; nup98 hoxa9 ... See more keywords
Molecular pathogenesis of Cryptosporidium and advancements in therapeutic interventions
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DOI: 10.1051/parasite/2025001
Abstract: Cryptosporidiosis, caused by a Cryptosporidium infection, is a serious gastrointestinal disease commonly leading to diarrhea in humans. This disease poses a particular threat to infants, young children, and those with weakened immune systems. The treatment… read more here.
Keywords: molecular pathogenesis; cryptosporidium advancements; pathogenesis cryptosporidium; cryptosporidium ... See more keywords
Molecular Pathogenesis of Ovarian Endometrioma: Mechanistic Insights and Therapeutic Implications.
Sign Up to like & getrecommendations! Published in 2025 at "Biology of reproduction"
DOI: 10.1093/biolre/ioaf219
Abstract: Ovarian endometrioma (OMA), the most prevalent and clinically consequential subtype of endometriosis, represents a chronic inflammatory disorder characterized by ectopic endometrial-like lesions. This condition manifests as progressive dysmenorrhea, ovarian reserve depletion, and subfertility, imposing substantial… read more here.
Keywords: ovarian endometrioma; endometrioma; molecular pathogenesis; endometrioma mechanistic ... See more keywords
Comprehensive bioinformatics analysis of trabecular meshwork gene expression data to unravel the molecular pathogenesis of primary open‐angle glaucoma
Sign Up to like & getrecommendations! Published in 2019 at "Acta Ophthalmologica"
DOI: 10.1111/aos.14154
Abstract: Performing bioinformatics analyses using trabecular meshwork (TM) gene expression data in order to further elucidate the molecular pathogenesis of primary open‐angle glaucoma (POAG), and to identify candidate target genes. read more here.
Keywords: trabecular meshwork; meshwork gene; expression data; pathogenesis primary ... See more keywords
Aplastic anemia: Etiology, molecular pathogenesis, and emerging concepts
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DOI: 10.1111/ejh.13153
Abstract: Aplastic anemia (AA) is rare disorder of bone marrow failure which if severe and not appropriately treated is highly fatal. AA is characterized by morphologic marrow features, namely hypocellularity, and resultant peripheral cytopenias. The molecular… read more here.
Keywords: aplastic anemia; etiology; molecular pathogenesis; pathogenesis ... See more keywords
Molecular pathogenesis of acquired aplastic anemia
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DOI: 10.1111/ejh.13182
Abstract: The application of next‐generation sequencing (NGS) has enhanced our understanding of the genetic landscape in acquired aplastic anemia (AA). Parallel progress has been in addressing aspects underlying immune dysregulation in disease pathogenesis. Novel insights into… read more here.
Keywords: pathogenesis acquired; acquired aplastic; aplastic anemia; molecular pathogenesis ... See more keywords
Recent advances in the diagnosis, classification and molecular pathogenesis of cutaneous mesenchymal neoplasms
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DOI: 10.1111/his.14450
Abstract: The diagnosis of cutaneous mesenchymal neoplasms remains challenging, due to a combination of overlapping histological features, the rarity of some diagnoses and often inadequate sampling in superficial biopsies. Here, we describe recent advances in cutaneous… read more here.
Keywords: histopathology; molecular pathogenesis; diagnosis; recent advances ... See more keywords
Molecular pathogenesis and heterogeneity in type 3 VWD families in U.S. Zimmerman program
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.15713
Abstract: Type 3 von Willebrand Disease (VWD) is a rare and severe form of VWD characterized by the absence of von Willebrand factor (VWF). read more here.
Keywords: vwd; molecular pathogenesis; heterogeneity type; type ... See more keywords