The ins and outs of molecular pathology reporting
Sign Up to like & getrecommendations! Published in 2017 at "Virchows Archiv"
DOI: 10.1007/s00428-017-2108-0
Abstract: The raid evolution in molecular pathology resulting in an increasing complexity requires careful reporting. The need for standardisation is clearer than ever. While synoptic reporting was first used for reporting hereditary genetic diseases, it is… read more here.
Keywords: reporting; ins outs; pathology; outs molecular ... See more keywords
“The leading role of pathology in assessing the somatic molecular alterations of cancer: Position Paper of the European Society of Pathology”: letter to the Editor
Sign Up to like & getrecommendations! Published in 2020 at "Virchows Archiv"
DOI: 10.1007/s00428-020-02898-2
Abstract: To the Editor: In a recent Virchows Archiv publication,Matias-Guiu et al. [1] indicate the central role for pathology in oncology molecular diagnostics. Motivated by this publication, we would like to make several comments. First, the… read more here.
Keywords: pathology; role pathology; molecular pathology; oncology ... See more keywords
Molecular pathology of rare progeroid diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Trends in molecular medicine"
DOI: 10.1016/j.molmed.2021.06.011
Abstract: Progeroid syndromes (PSs) are characterized by the premature onset of age-related pathologies. The genetic mutations underlying PSs are functionally linked to genome maintenance and repair, supporting the causative role of DNA damage accumulation in aging.… read more here.
Keywords: progeroid diseases; rare progeroid; age related; pathology ... See more keywords
Glutamate transport system as a key constituent of glutamosome: Molecular pathology and pharmacological modulation in chronic pain
Sign Up to like & getrecommendations! Published in 2019 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2019.04.029
Abstract: Neural uptake of glutamate is executed by the structurally related members of the SLC1A family of solute transporters: GLAST/EAAT1, GLT-1/EAAT2, EAAC1/EAAT3, EAAT4, ASCT2. These plasma membrane proteins ensure supply of glutamate, aspartate and some neutral… read more here.
Keywords: transport; pathology; molecular pathology; glutamate ... See more keywords
Molecular Pathology of Bone Tumors: What Have We Learned and How Does It Affect Daily Practice?
Sign Up to like & getrecommendations! Published in 2017 at "Surgical pathology clinics"
DOI: 10.1016/j.path.2017.06.001
Abstract: .c om Bone tumors are often found to be difficult by pathologists, because they are rare, and in total, almost 60 entities are recognized with considerable morphologic overlap. Similar to the classification of soft tissue… read more here.
Keywords: bone tumors; soft tissue; pathology; bone ... See more keywords
Immunohistochemistry features and molecular pathology of appendiceal neoplasms
Sign Up to like & getrecommendations! Published in 2021 at "Critical Reviews in Clinical Laboratory Sciences"
DOI: 10.1080/10408363.2021.1881756
Abstract: Abstract Primary appendiceal neoplasms (ANs) comprise a heterogeneous group of tumors. The pathology and classification of ANs have been controversial, and thus, a new classification of these neoplasms was published in the World Health Organization… read more here.
Keywords: classification; pathology; appendiceal neoplasms; expression ... See more keywords
Molecular pathology and clinical implications of diffuse glioma
Sign Up to like & getrecommendations! Published in 2022 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000002446
Abstract: Abstract The prognosis for diffusely infiltrating gliomas at World Health Organization (WHO) grade 2–4 remains dismal due to their heterogeneity. The rapid development of genome-wide molecular-profiling-associated studies has greatly promoted the accuracy of glioma classification.… read more here.
Keywords: clinical implications; diffuse glioma; implications diffuse; molecular pathology ... See more keywords
Locus coeruleus cellular and molecular pathology during the progression of Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neuropathologica Communications"
DOI: 10.1186/s40478-017-0411-2
Abstract: A major feature of Alzheimer’s disease (AD) is the loss of noradrenergic locus coeruleus (LC) projection neurons that mediate attention, memory, and arousal. However, the extent to which the LC projection system degenerates during the… read more here.
Keywords: alzheimer disease; disease; pathology; locus coeruleus ... See more keywords
Editorial: Molecular Pathology of HTLV-1
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2018.03069
Abstract: Human T-cell leukemia virus type 1 (HTLV-1) was the first human retrovirus discovered. It is estimated that 10–20 million people are infected worldwide by this oncogenic virus. About 5–10% of HTLV-1-infected individuals are at risk… read more here.
Keywords: htlv; editorial molecular; pathology; pathology htlv ... See more keywords
A growing understanding of the role of muscarinic receptors in the molecular pathology and treatment of schizophrenia
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2023.1124333
Abstract: Pre-clinical models, postmortem and neuroimaging studies all support a role for muscarinic receptors in the molecular pathology of schizophrenia. From these data it was proposed that activation of the muscarinic M1 and/or M4 receptor would… read more here.
Keywords: muscarinic receptors; molecular pathology; pathology; receptors molecular ... See more keywords
Retinitis Pigmentosa: Progress in Molecular Pathology and Biotherapeutical Strategies
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23094883
Abstract: Retinitis pigmentosa (RP) is genetically heterogeneous retinopathy caused by photoreceptor cell death and retinal pigment epithelial atrophy that eventually results in blindness in bilateral eyes. Various photoreceptor cell death types and pathological phenotypic changes that… read more here.
Keywords: cell; retinitis pigmentosa; molecular pathology; pathology ... See more keywords