A novel DNA methylation panel accurately detects colorectal cancer independently of molecular pathway
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-018-1415-9
Abstract: BackgroundColorectal cancer (CRC) is one of the most incident cancers, associated with significant morbidity and mortality, and usually classified into three main molecular pathways: chromosomal instability, microsatellite instability (MSI) and CpG island methylator phenotype (CIMP).… read more here.
Keywords: methylation; promoter methylation; molecular pathway; cancer ... See more keywords
General intelligence and executive functioning are overlapping but separable at genetic and molecular pathway levels: An analytical review of existing GWAS findings
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0272368
Abstract: Understanding the genomic architecture and molecular mechanisms of cognitive functioning in healthy individuals is critical for developing tailored interventions to enhance cognitive functioning, as well as for identifying targets for treating impaired cognition. There has… read more here.
Keywords: executive functioning; molecular pathway; review existing; overlapping separable ... See more keywords
A Community-Driven, Openly Accessible Molecular Pathway Integrating Knowledge on Malignant Pleural Mesothelioma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.849640
Abstract: Malignant pleural mesothelioma (MPM) is a highly aggressive malignancy mainly triggered by exposure to asbestos and characterized by complex biology. A significant body of knowledge has been generated over the decades by the research community… read more here.
Keywords: malignant pleural; community; pleural mesothelioma; knowledge ... See more keywords