Update of Antitubercular Prodrugs from a Molecular Perspective: Mechanisms of Action, Bioactivation Pathways, and Associated Resistance
Sign Up to like & getrecommendations! Published in 2017 at "ChemMedChem"
DOI: 10.1002/cmdc.201700424
Abstract: The place of prodrugs in the current antitubercular therapeutic arsenal is preponderant, since two of the four first‐line antitubercular agents, isoniazid (INH) and pyrazinamide (PZA), need to be activated by Mycobacterium tuberculosis before exerting their… read more here.
Keywords: molecular perspective; update antitubercular; resistance; activation ... See more keywords
Competitive Interactions at Electrolyte/Octanol Interfaces: A Molecular Perspective
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Physical Chemistry C"
DOI: 10.1021/acs.jpcc.0c00302
Abstract: Much is understood about electrolyte liquid/liquid interfaces, yet the relationships between ion solvation, adsorption, and the instantaneous surface have not been the topic of significant study. T... read more here.
Keywords: octanol interfaces; competitive interactions; interfaces molecular; molecular perspective ... See more keywords
Magnetic cooling: a molecular perspective.
Sign Up to like & getrecommendations! Published in 2022 at "Dalton transactions"
DOI: 10.1039/d2dt01565j
Abstract: The magnetocaloriceffect is considered as an energy-efficient and environmentally friendly technique which can take cooling technology to the next level. Apart from its commercial application at room temperature, magnetic refrigeration is an up-and-coming solution for… read more here.
Keywords: molecular perspective; magnetocaloric effect; magnetic cooling; cooling molecular ... See more keywords
Cytotoxic Chemotherapy as an Immune Stimulus: A Molecular Perspective on Turning Up the Immunological Heat on Cancer
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.01654
Abstract: Cytotoxic chemotherapeutics (CCTs) are widely used in the treatment of cancer. Although their mechanisms of action have been best understood in terms of targeting the apparatus of mitosis, an ability to stimulate anti-tumor immune responses… read more here.
Keywords: immune stimulus; molecular perspective; anti tumor; cancer ... See more keywords
The Biological Activities of Oleocanthal from a Molecular Perspective
Sign Up to like & getrecommendations! Published in 2018 at "Nutrients"
DOI: 10.3390/nu10050570
Abstract: Oleocanthal is a minor constituent of olive oil with strong anti-inflammatory activities. Since the pathogenesis of many chronic diseases involves inflammatory and oxidative components, oleocanthal is a promising agent to prevent these conditions. This review… read more here.
Keywords: activities oleocanthal; effects oleocanthal; biological activities; molecular perspective ... See more keywords