Molecular pharmacology of GPCRs
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Pharmacology"
DOI: 10.1111/bph.14474
Abstract: This article is part of a themed section on Molecular Pharmacology of GPCRs. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v175.21/issuetoc read more here.
Keywords: pharmacology gpcrs; pharmacology; molecular pharmacology;
Advances in the molecular pharmacology of bone and cancer‐related bone diseases
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15431
Abstract: Over recent years, our understanding of the mechanisms that drive bone disorders has dramatically increased, supported by advances in technology that facilitate the dissection of the cellular and molecular crosstalk that underpins disease pathogenesis. This… read more here.
Keywords: molecular pharmacology; bone; pharmacology; bone disease ... See more keywords
Molecular Pharmacology and Novel Potential Therapeutic Applications of Fingolimod
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.807639
Abstract: Fingolimod is a well-tolerated, highly effective disease-modifying therapy successfully utilized in the management of multiple sclerosis. The active metabolite, fingolimod-phosphate, acts on sphingosine-1-phosphate receptors (S1PRs) to bring about an array of pharmacological effects. While being… read more here.
Keywords: molecular pharmacology; novel potential; potential therapeutic; fingolimod ... See more keywords
Molecular Pharmacology of P2X Receptors: Exploring Druggable Domains Revealed by Structural Biology
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.925880
Abstract: Extracellular ATP is a critical signaling molecule that is found in a wide range of concentrations across cellular environments. The family of nonselective cation channels that sense extracellular ATP, termed P2X receptors (P2XRs), is composed… read more here.
Keywords: structural biology; pharmacology; p2x receptors; extracellular atp ... See more keywords
The Molecular Pharmacology of Phloretin: Anti-Inflammatory Mechanisms of Action
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11010143
Abstract: The isolation of phlorizin from the bark of an apple tree in 1835 led to a flurry of research on its inhibitory effect on glucose transporters in the intestine and kidney. Using phlorizin as a… read more here.
Keywords: inflammatory mechanisms; pharmacology phloretin; pharmacology; anti inflammatory ... See more keywords
Artemisinin-Based Antimalarial Drug Therapy: Molecular Pharmacology and Evolving Resistance
Sign Up to like & getrecommendations! Published in 2019 at "Tropical Medicine and Infectious Disease"
DOI: 10.3390/tropicalmed4020089
Abstract: The molecular pharmacology of artemisinin (ART)-based antimalarial drugs is incompletely understood. Clinically, these drugs are used in combination with longer lasting partner drugs in several different artemisinin combination therapies (ACTs). ACTs are currently the standard… read more here.
Keywords: based antimalarial; molecular pharmacology; pharmacology; resistance ... See more keywords
Architecture of the molecules of life, a contribution of Louis Pasteur to molecular pharmacology; opportunities for adrenergic pharmacology developments
Sign Up to like & getrecommendations! Published in 2020 at "Comptes Rendus Chimie"
DOI: 10.5802/crchim.2
Abstract: When Louis Pasteur observed para tartaric acid crystals under the microscope, he noted rightand left-handed tiny crystals, which when manually separated resulted in the same optical activity but of opposite sign. This seminal observation was… read more here.
Keywords: molecular pharmacology; architecture molecules; pasteur; pharmacology ... See more keywords