Prevalence of pathogenic mismatch repair mutations in an Irish cohort after clinical and molecular pre-selection.
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DOI: 10.1200/jco.2017.35.4_suppl.574
Abstract: 574Background: Lynch syndrome (LS) is a highly penetrant, autosomal dominant multi-system disorder characterised by an inherited predisposition to a range of cancers. LS is caused by germline mutations in one of the mismatch repair (MMR)… read more here.
Keywords: molecular pre; pre selection; prevalence pathogenic; irish cohort ... See more keywords