Recent Advances of Activatable Molecular Probes Based on Semiconducting Polymer Nanoparticles in Sensing and Imaging
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Science"
DOI: 10.1002/advs.201600481
Abstract: Molecular probes that change their signals in response to the target of interest have a critical role in fundamental biology and medicine. Semiconducting polymer nanoparticles (SPNs) have recently emerged as a new generation of purely… read more here.
Keywords: sensing imaging; semiconducting polymer; recent advances; activatable molecular ... See more keywords
Current strategies for the development of fluorescence-based molecular probes for visualizing the enzymes and proteins associated with Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2021 at "Coordination Chemistry Reviews"
DOI: 10.1016/j.ccr.2020.213553
Abstract: Abstract One of the most prevalent forms of dementia is Alzheimer's disease (AD) which causes severe memory impairment within humans. As such, research into the early diagnosis of AD is essential to help treatment, which… read more here.
Keywords: current strategies; fluorescence; alzheimer disease; enzymes proteins ... See more keywords
Molecular probes for human cytochrome P450 enzymes: Recent progress and future perspectives
Sign Up to like & getrecommendations! Published in 2021 at "Coordination Chemistry Reviews"
DOI: 10.1016/j.ccr.2020.213600
Abstract: Abstract The cytochrome P450 enzymes (P450s or CYPs) are a class of heme-containing monooxygenases responsible for the oxidative metabolism of a wide range of endogenous substances and foreign chemicals. Deciphering the physiological functions of CYPs… read more here.
Keywords: cytochrome p450; probes human; p450 enzymes; probe substrates ... See more keywords
Characterization of nanomedicines’ surface coverage using molecular probes and capillary electrophoresis
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2018.06.014
Abstract: ABSTRACT A faithful characterization of nanomedicine (NM) is needed for a better understanding of their in vivo outcomes. Size and surface charge are studied with well‐established methods. However, other relevant parameters for the understanding of… read more here.
Keywords: capillary electrophoresis; surface; surface coverage; molecular probes ... See more keywords
A silver nanosol SERS quantitative method for trace F− detection using the oxidized tetramethylbenzidine as molecular probes
Sign Up to like & getrecommendations! Published in 2020 at "Microchemical Journal"
DOI: 10.1016/j.microc.2019.104439
Abstract: Abstract Fluoride constitutes an essential component for the formation of hard bones and teeth. However long-term excessive intake of fluoride causes chronic poisoning changes in the body. Therefore, the determination of its content is of… read more here.
Keywords: detection; sers quantitative; trace; method ... See more keywords
Imim-DEHP reverse micelles investigated with two molecular probes reveals how are the interfacial properties and the coordination behavior of the surfactant
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2020.113592
Abstract: Abstract Aqueous reverse micelles (RMs) generated with the ionic liquid (IL)-surfactant 1-methylimidazolium bis-(2-ethylhexyl)phosphate (imim-DEHP) and the biocompatible solvents methyl laurate (ML) and isopropyl myristate (IPM) were studied through the use of two molecular probes: the… read more here.
Keywords: dehp; two molecular; imim dehp; molecular probes ... See more keywords
Analysis of Metabolic Pathways by 13C-Labeled Molecular Probes and HRMAS Nuclear Magnetic Resonance Spectroscopy: Isotopologue Identification and Quantification Methods for Medical Applications.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c00214
Abstract: The use of 13C-labeled molecular probes is essential to explore altered metabolic pathways in human pathologies. The analysis of the different 13C isotopologues resulting from these changes in metabolic pathways is essential to understand the… read more here.
Keywords: labeled molecular; 13c labeled; methodology; spectroscopy ... See more keywords
Molecular Probes, Chemosensors, and Nanosensors for Optical Detection of Biorelevant Molecules and Ions in Aqueous Media and Biofluids
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Reviews"
DOI: 10.1021/acs.chemrev.1c00746
Abstract: Synthetic molecular probes, chemosensors, and nanosensors used in combination with innovative assay protocols hold great potential for the development of robust, low-cost, and fast-responding sensors that are applicable in biofluids (urine, blood, and saliva). Particularly,… read more here.
Keywords: probes chemosensors; media biofluids; chemosensors nanosensors; detection ... See more keywords
Molecular Probes Reveal Chemical Selectivity of the Solid–Electrolyte Interphase
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Physical Chemistry C"
DOI: 10.1021/acs.jpcc.8b06564
Abstract: The solid–electrolyte interphase (SEI) is well-known to provide critical protection between the strongly reducing negative electrode and the organic electrolytes of nonaqueous batteries. Batteries with a poorly passivating SEI will suffer from rapid capacity fade… read more here.
Keywords: electrolyte interphase; solid electrolyte; probes reveal; molecular probes ... See more keywords
Integrating molecular probes and molecular dynamics to reveal binding modes of GLUT5 activatory and inhibitory ligands.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical communications"
DOI: 10.1039/c8cc04843f
Abstract: Fructose transporter GLUT5 is characterized by unusual substrate specificity and is linked to a variety of metabolic disorders. A series of high-affinity GLUT5-specific sugar-based probes - ManCous - have been very recently described and efficiently… read more here.
Keywords: reveal binding; molecular dynamics; probes molecular; integrating molecular ... See more keywords
5′-fluoro(di)phosphate-labeled oligonucleotides are versatile molecular probes for studying nucleic acid secondary structure and interactions by 19F NMR
Sign Up to like & getrecommendations! Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaa470
Abstract: Abstract The high sensitivity of 19F nucleus to changes in the chemical environment has promoted the use of fluorine-labeled molecular probes to study structure and interactions of nucleic acids by 19F NMR. So far, most… read more here.
Keywords: secondary structure; structure interactions; molecular probes; structure ... See more keywords