Molecular profile of the rat peri-infarct region four days after stroke: Study with MANF
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2020.113288
Abstract: The peri-infarct region after ischemic stroke is the anatomical location for many of the endogenous recovery processes, and the molecular events in the peri-infarct region remain poorly characterized. In this study, we examine the molecular… read more here.
Keywords: manf; infarct region; peri infarct; molecular profile ... See more keywords
P1.02-085 Molecular Profile in NSCLC Biopsy Samples: A Multicenter Local Study: Topic: Other Mutations in Thoracic Malignancies
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Thoracic Oncology"
DOI: 10.1016/j.jtho.2016.11.669
Abstract: in abrogating G2-M cell cycle arrest in the presence of mutational alterations may be central to progression of premalignant airway lesions to invasive SCC. Methods: Cultures of the bronchial epithelium derived BEAS-2B (B2B) cell linewere… read more here.
Keywords: mutation; 085 molecular; presence; nsclc biopsy ... See more keywords
Molecular profile of FLT3-mutated relapsed/refractory patients with AML in the phase 3 ADMIRAL study of gilteritinib
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2021006489
Abstract: Key Points Patients with FLT3-mutated R/R AML benefitted from gilteritinib regardless of comutations, FLT3-ITD allelic ratio, or FLT3-ITD length. Resistance to gilteritinib was associated with acquired Ras/MAPK pathway gene mutations and FLT3 F691L mutations. read more here.
Keywords: flt3; molecular profile; flt3 mutated; mutated relapsed ... See more keywords
Outcomes and molecular profile of oligomonocytic CMML support its consideration as the first stage in the CMML continuum
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2022007359
Abstract: Key Points Patients with OM-CMML presented longer OS and acute myeloid leukemia–free survival than did those with D-CMML or P-CMML. The progression of a high proportion of OM-CMML into D-CMML and D-CMML into P-CMML reinforces… read more here.
Keywords: cmml cmml; molecular profile; profile oligomonocytic; cmml ... See more keywords
Molecular profile of glioblastoma as perspective of targeted therapy.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e14037
Abstract: e14037Background: Glioblastoma is one of the most malignant forms of cancer, for which no effective therapy has been found. Although numerous genomic studies has provided a list of fusion genes in ... read more here.
Keywords: glioblastoma perspective; targeted therapy; profile glioblastoma; therapy ... See more keywords
The molecular profile of the inflammatory process differs among various neurodevelopmental disorders with or without cognitive component: A hypothesis of persistent systemic dysfunction and hyper-resolution
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2023.1132175
Abstract: Introduction Challenges of diverse origin in childhood can alter the growth and development of the central nervous system, affecting structures and functions. As a consequence of the damage suffered during the perinatal period, long periods… read more here.
Keywords: molecular profile; dysfunction; profile inflammatory; inflammatory process ... See more keywords
Molecular Profile Study of Extracellular Vesicles for the Identification of Useful Small “Hit” in Cancer Diagnosis
Sign Up to like & getrecommendations! Published in 2021 at "Applied Sciences"
DOI: 10.3390/app112210787
Abstract: Tumor-secreted extracellular vesicles (EVs) are the main mediators of cell-cell communication, permitting cells to exchange proteins, lipids, and metabolites in varying physiological and pathological conditions. They contain signature tumor-derived molecules that reflect the intracellular status… read more here.
Keywords: cancer; tumor; extracellular vesicles; diagnosis ... See more keywords
Genotype-to-Phenotype Associations in the Aggressive Variant Prostate Cancer Molecular Profile (AVPC-m) Components
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14133233
Abstract: Simple Summary We treat prostate cancer like it is one disease, but it is clear that it behaves like different diseases in different patients, with some having excellent responses to hormonal therapies and prolonged survivals,… read more here.
Keywords: prostate; avpc; prostate cancer; molecular profile ... See more keywords
Current Molecular Profile of Gastrointestinal Stromal Tumors and Systemic Therapeutic Implications
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14215330
Abstract: Simple Summary Gastrointestinal stromal tumors (GISTs) are malignant mesenchymal tumors classified primarily as soft tissue sarcomas and characteristically arise from the intestinal pacemaker cells of Cajal responsible for the gastrointestinal tract motility. They comprise a… read more here.
Keywords: molecular profile; stromal tumors; systemic therapeutic; therapeutic implications ... See more keywords
Molecular profile and clinical features of patients with gliomas using a broad targeted next generation-sequencing panel.
Sign Up to like & getrecommendations! Published in 2022 at "Oncology letters"
DOI: 10.3892/ol.2022.13624
Abstract: Gliomas are the most common malignant primary brain tumors characterized by poor prognosis. The genotyping of tumors using next generation sequencing (NGS) platforms enables the identification of genetic alterations that constitute diagnostic, prognostic and predictive… read more here.
Keywords: molecular profile; panel identified; panel; next generation ... See more keywords