Characterization of rare histological subtypes of ovarian cancer based on molecular profiling
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4927
Abstract: Pan‐cancer analysis across The Cancer Genome Atlas has revealed the molecular profiles of major types of carcinomas. High‐grade serous carcinomas (HGSCs) have been characterized; however, in ovarian cancer, the profile of carcinoma with minor histopathological… read more here.
Keywords: ovarian cancer; rare histological; characterization rare; histological subtypes ... See more keywords
Molecular profiling of colorectal cancer in a genetically admixed Hispanic population.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.5888
Abstract: Colorectal cancer (CRC) is among the leading causes of cancer‐related deaths among Hispanics living in the United States (USH). Understanding the most common carcinogenic molecular pathways that affect Hispanics with CRC is crucial to guide… read more here.
Keywords: genetically admixed; cancer genetically; colorectal cancer; profiling colorectal ... See more keywords
Histology‐based molecular profiling improves mutation detection for advanced thyroid cancer
Sign Up to like & getrecommendations! Published in 2021 at "Genes"
DOI: 10.1002/gcc.22949
Abstract: Advanced cancers frequently show histologic and molecular intratumoral heterogeneity. Therefore, we comprehensively characterized advanced, metastatic, radioiodine‐resistant (RAIR) thyroid carcinomas at the molecular level in the context of histologic heterogeneity with the aim to identify potentially… read more here.
Keywords: histology; heterogeneity; molecular profiling; thyroid cancer ... See more keywords
In Vivo Molecular Profiling of Human Glioma
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Neuroradiology"
DOI: 10.1007/s00062-018-0676-2
Abstract: PurposeTo assess the diagnostic performance of dynamic susceptibility contrast perfusion magnetic resonance perfusion imaging (DSC-MRI) for in vivo human glioma molecular profiling.MethodsIn this study 100 patients with histopathologically confirmed glioma who provided written informed consent were… read more here.
Keywords: human glioma; diagnostic performance; glioma; vivo ... See more keywords
Colorectal cancer molecular profiling: from IHC to NGS in search of optimal algorithm
Sign Up to like & getrecommendations! Published in 2017 at "Virchows Archiv"
DOI: 10.1007/s00428-017-2153-8
Abstract: Advances in defining the mutational landscape of colorectal cancer (CRC) over the past decades have revolutionized the molecular understanding and clinical testing algorithms for this disease. Mutation testing is standard of care for the work-up… read more here.
Keywords: colorectal cancer; molecular profiling; profiling ihc; cancer ... See more keywords
Clinical, pathologic, cytogenetic, and molecular profiling in self-identified black women with uterine leiomyomata.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer genetics"
DOI: 10.1016/j.cancergen.2018.01.001
Abstract: Black women are disproportionately affected by uterine leiomyomata (UL), or fibroids, compared to other racial groups, having a greater lifetime risk of developing UL and an earlier age of diagnosis. In order to elucidate molecular… read more here.
Keywords: black women; clinical pathologic; molecular profiling; pathologic cytogenetic ... See more keywords
Molecular profiling of vitreous fluid by massively parallel sequencing: a case series.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Society of Cytopathology"
DOI: 10.1016/j.jasc.2020.03.005
Abstract: INTRODUCTION In cases of suspected intraocular malignancy, vitreous may be the preferred pathologic sample; however, cellularity may be insufficient for definitive cytopathological diagnosis. Ancillary methodology to study vitreous fluid aspiration for mutational analysis may assist… read more here.
Keywords: massively parallel; molecular profiling; case; vitreous fluid ... See more keywords
Precise Molecular Profiling of Circulating Exosomes Using a Metal-Organic Framework-Based Sensing Interface and an Enzyme-Based Electrochemical Logic Platform.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c03644
Abstract: Exosomes have emerged as a promising circulating tumor biomarker; however, it is a big challenge for convenient, multiparametric, and accurate profiling of tumorous exosomes due to their unique structure and heterogeneity. To address these problems,… read more here.
Keywords: enzyme based; platform; organic framework; sensing interface ... See more keywords
All-in-One Strategy for Downstream Molecular Profiling of Tumor-Derived Exosomes.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c07143
Abstract: In light of the significance of exosomes in cancer diagnosis and treatment, it is important to understand the components and functions of exosomes. Herein, an all-in-one strategy has been proposed for comprehensive characterization of exosomal… read more here.
Keywords: downstream molecular; analysis; strategy; one strategy ... See more keywords
Molecular profiling of driver events in metastatic uveal melanoma
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-15606-0
Abstract: Metastatic uveal melanoma is less well understood than its primary counterpart, has a distinct biology compared to skin melanoma, and lacks effective treatments. Here we genomically profile metastatic tumors and infiltrating lymphocytes. BAP1 alterations are… read more here.
Keywords: melanoma; molecular profiling; uveal melanoma; metastatic uveal ... See more keywords
Profiling of lymphoma from formalin-fixed paraffin-embedded tissue.
Sign Up to like & getrecommendations! Published in 2019 at "Seminars in hematology"
DOI: 10.1053/j.seminhematol.2018.05.003
Abstract: Molecular profiling of lymphoma samples has contributed enormously to our understanding of disease biology leading to detailed descriptions of diagnostic categories. These studies have also helped the field to recognize different subtypes of disease, different… read more here.
Keywords: fixed paraffin; profiling lymphoma; paraffin embedded; molecular profiling ... See more keywords