Molecular Profiling Defines Three Subtypes of Synovial Sarcoma
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202404510
Abstract: Synovial Sarcomas (SS) are characterized by the presence of the SS18::SSX fusion gene, which protein product induce chromatin changes through remodeling of the BAF complex. To elucidate the genomic events that drive phenotypic diversity in… read more here.
Keywords: molecular profiling; defines three; profiling defines; subtypes synovial ... See more keywords
Characterization of rare histological subtypes of ovarian cancer based on molecular profiling
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4927
Abstract: Pan‐cancer analysis across The Cancer Genome Atlas has revealed the molecular profiles of major types of carcinomas. High‐grade serous carcinomas (HGSCs) have been characterized; however, in ovarian cancer, the profile of carcinoma with minor histopathological… read more here.
Keywords: ovarian cancer; rare histological; characterization rare; histological subtypes ... See more keywords
Molecular profiling of colorectal cancer in a genetically admixed Hispanic population.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.5888
Abstract: Colorectal cancer (CRC) is among the leading causes of cancer‐related deaths among Hispanics living in the United States (USH). Understanding the most common carcinogenic molecular pathways that affect Hispanics with CRC is crucial to guide… read more here.
Keywords: genetically admixed; cancer genetically; colorectal cancer; profiling colorectal ... See more keywords
Histology‐based molecular profiling improves mutation detection for advanced thyroid cancer
Sign Up to like & getrecommendations! Published in 2021 at "Genes"
DOI: 10.1002/gcc.22949
Abstract: Advanced cancers frequently show histologic and molecular intratumoral heterogeneity. Therefore, we comprehensively characterized advanced, metastatic, radioiodine‐resistant (RAIR) thyroid carcinomas at the molecular level in the context of histologic heterogeneity with the aim to identify potentially… read more here.
Keywords: histology; heterogeneity; molecular profiling; thyroid cancer ... See more keywords
Clinical and Molecular Profiling in GNAO1 Permits Phenotype–Genotype Correlation
Sign Up to like & getrecommendations! Published in 2024 at "Movement Disorders"
DOI: 10.1002/mds.29881
Abstract: Defects in GNAO1, the gene encoding the major neuronal G‐protein Gαo, are related to neurodevelopmental disorders, epilepsy, and movement disorders. Nevertheless, there is a poor understanding of how molecular mechanisms explain the different phenotypes. read more here.
Keywords: molecular profiling; profiling gnao1; clinical molecular; permits phenotype ... See more keywords
In Vivo Molecular Profiling of Human Glioma
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Neuroradiology"
DOI: 10.1007/s00062-018-0676-2
Abstract: PurposeTo assess the diagnostic performance of dynamic susceptibility contrast perfusion magnetic resonance perfusion imaging (DSC-MRI) for in vivo human glioma molecular profiling.MethodsIn this study 100 patients with histopathologically confirmed glioma who provided written informed consent were… read more here.
Keywords: human glioma; diagnostic performance; glioma; vivo ... See more keywords
Molecular profiling of cell-free DNA from classic Hodgkin lymphoma patients identifies potential prognostic clusters and corresponds with disease dynamics
Sign Up to like & getrecommendations! Published in 2025 at "Annals of Hematology"
DOI: 10.1007/s00277-025-06328-8
Abstract: Cell-free DNA (cfDNA) analysis has advantages over tissue analysis for molecular profiling of classic Hodgkin lymphoma (cHL) at diagnosis and offers additional opportunities for sensitive non-invasive disease tracking during treatment. The aim of this study… read more here.
Keywords: disease; classic hodgkin; molecular profiling; free dna ... See more keywords
Colorectal cancer molecular profiling: from IHC to NGS in search of optimal algorithm
Sign Up to like & getrecommendations! Published in 2017 at "Virchows Archiv"
DOI: 10.1007/s00428-017-2153-8
Abstract: Advances in defining the mutational landscape of colorectal cancer (CRC) over the past decades have revolutionized the molecular understanding and clinical testing algorithms for this disease. Mutation testing is standard of care for the work-up… read more here.
Keywords: colorectal cancer; molecular profiling; profiling ihc; cancer ... See more keywords
Clinical, pathologic, cytogenetic, and molecular profiling in self-identified black women with uterine leiomyomata.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer genetics"
DOI: 10.1016/j.cancergen.2018.01.001
Abstract: Black women are disproportionately affected by uterine leiomyomata (UL), or fibroids, compared to other racial groups, having a greater lifetime risk of developing UL and an earlier age of diagnosis. In order to elucidate molecular… read more here.
Keywords: black women; clinical pathologic; molecular profiling; pathologic cytogenetic ... See more keywords
Molecular profiling of vitreous fluid by massively parallel sequencing: a case series.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Society of Cytopathology"
DOI: 10.1016/j.jasc.2020.03.005
Abstract: INTRODUCTION In cases of suspected intraocular malignancy, vitreous may be the preferred pathologic sample; however, cellularity may be insufficient for definitive cytopathological diagnosis. Ancillary methodology to study vitreous fluid aspiration for mutational analysis may assist… read more here.
Keywords: massively parallel; molecular profiling; case; vitreous fluid ... See more keywords
Precise Molecular Profiling of Circulating Exosomes Using a Metal-Organic Framework-Based Sensing Interface and an Enzyme-Based Electrochemical Logic Platform.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c03644
Abstract: Exosomes have emerged as a promising circulating tumor biomarker; however, it is a big challenge for convenient, multiparametric, and accurate profiling of tumorous exosomes due to their unique structure and heterogeneity. To address these problems,… read more here.
Keywords: enzyme based; platform; organic framework; sensing interface ... See more keywords