Development of a calibration protocol for quantitative imaging for molecular radiotherapy dosimetry
Sign Up to like & getrecommendations! Published in 2017 at "Radiation Physics and Chemistry"
DOI: 10.1016/j.radphyschem.2017.02.053
Abstract: Abstract Within the field of molecular radiotherapy, there is a significant need for standardisation in dosimetry, in both quantitative imaging and dosimetry calculations. Currently, there are a wide range of techniques used by different clinical… read more here.
Keywords: protocol; molecular radiotherapy; imaging; quantitative imaging ... See more keywords
A kinetic model of continuous radiation damage to populations of cells: comparison to the LQ model and application to molecular radiotherapy.
Sign Up to like & getrecommendations! Published in 2020 at "Physics in medicine and biology"
DOI: 10.1088/1361-6560/aba21d
Abstract: The linear-quadratic (LQ) model to describe the survival of irradiated cells may be the most frequently used biomathematical model in radiotherapy. There has been an intense debate on the mechanistic origin of the LQ model.… read more here.
Keywords: radiotherapy; molecular radiotherapy; model; application ... See more keywords
Overall survival after 177Lu-PSMA-617 molecular radiotherapy in patients with metastatic castrate-resistant prostate cancer: Post-hoc analysis of a prospective phase II trial.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.5549
Abstract: 5549Background: This was an open-label randomized prospective bi-centric single-arm phase II clinical trial of 177Lu-PSMA-617 molecular radiotherapy in patients with progressive metastatic castrate... read more here.
Keywords: psma 617; 177lu psma; radiotherapy patients; metastatic castrate ... See more keywords
Molecular Radiotherapy with 177Lu-Immunoliposomes Induces Cytotoxicity in Mesothelioma Cancer Stem Cells In Vitro
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23073914
Abstract: Malignant mesothelioma (MM) is a lethal tumor originating in the mesothelium with high chemotherapeutic resistance. Cancer stem cells (CSCs) persist in tumors and are critical targets responsible for tumor resistance and recurrence. The identification and… read more here.
Keywords: radiotherapy 177lu; cancer stem; molecular radiotherapy; mesothelioma ... See more keywords
Personalisation of Molecular Radiotherapy through Optimisation of Theragnostics
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm10040174
Abstract: Molecular radiotherapy, or targeted radionuclide therapy, uses systemically administered drugs bearing a suitable radioactive isotope, typically a beta emitter. These are delivered via metabolic or other physiological pathways to cancer cells in greater concentrations than… read more here.
Keywords: personalisation molecular; radiotherapy; molecular radiotherapy; radiotherapy optimisation ... See more keywords