Novel molecular requirements for CRISPR RNA-guided transposition
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DOI: 10.1093/nar/gkad270
Abstract: Abstract CRISPR-associated transposases (CASTs) direct DNA integration downstream of target sites using the RNA-guided DNA binding activity of nuclease-deficient CRISPR-Cas systems. Transposition relies on several key protein-protein and protein-DNA interactions, but little is known about… read more here.
Keywords: dna; molecular requirements; integration; transposition ... See more keywords