Molecular signaling of ginsenosides Rb1, Rg1, and Rg3 and their mode of actions
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Ginseng Research"
DOI: 10.1016/j.jgr.2017.01.008
Abstract: Ginseng has gained its popularity as an adaptogen since ancient days because of its triterpenoid saponins, known as ginsenosides. These triterpenoid saponins are unique and classified as protopanaxatriol and protopanaxadiol saponins based on their glycosylation… read more here.
Keywords: signaling ginsenosides; ginsenosides rb1; molecular signaling; rg1 rg3 ... See more keywords
Streptozotocin induced hyperglycemia stimulates molecular signaling that promotes cell cycle reentry in mouse hippocampus
Sign Up to like & getrecommendations! Published in 2018 at "Life Sciences"
DOI: 10.1016/j.lfs.2018.05.019
Abstract: Aims: Cerebral atrophy resulting from neurodegeneration is highly prevalent in individuals with diabetes; however, the underlying mechanisms for diabetic neurodegeneration are not fully understood. Here we hypothesized that hyperglycemia induces molecular signaling that favors induction… read more here.
Keywords: streptozotocin induced; hippocampus; molecular signaling; cell cycle ... See more keywords
Extracellular vesicle mediated molecular signaling in ovarian follicle: Implication for oocyte developmental competence.
Sign Up to like & getrecommendations! Published in 2020 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2020.01.075
Abstract: The bidirectional communication between the oocyte and the companion somatic cells in the follicular environment is known to be mediated by either a direct communication via gap junction or transzonal projections or indirectly through endocrine,… read more here.
Keywords: extracellular vesicle; communication; molecular signaling; follicular growth ... See more keywords
Raman observation of a molecular signaling pathway of apoptotic cells induced by photothermal therapy† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc04389f
Sign Up to like & getrecommendations! Published in 2019 at "Chemical Science"
DOI: 10.1039/c9sc04389f
Abstract: A molecular signaling pathway of apoptosis induced by photothermal therapy was revealed by surface-enhanced Raman spectroscopy. read more here.
Keywords: molecular signaling; signaling pathway; induced photothermal; raman observation ... See more keywords
Biological events and molecular signaling following MLKL activation during necroptosis
Sign Up to like & getrecommendations! Published in 2017 at "Cell Cycle"
DOI: 10.1080/15384101.2017.1371889
Abstract: ABSTRACT Necroptosis is a form of programmed necrotic cell death mediated by the kinase RIPK3 and its substrate MLKL. MLKL, which displays plasma membrane (PM) pore-forming activity upon phosphorylation, functions as the executioner during necroptosis.… read more here.
Keywords: biological events; molecular signaling; necroptosis; activation ... See more keywords
Molecular signaling pathways as potential therapeutic targets in osteosarcoma.
Sign Up to like & getrecommendations! Published in 2022 at "Current medicinal chemistry"
DOI: 10.2174/0929867329666220209110009
Abstract: Among primary bone malignancies, osteosarcoma (OS) is the most common form causing morbidity and mortality in both adults and children. The interesting point about this malignancy is that nearly 10-20% of its newly diagnosed cases… read more here.
Keywords: targets osteosarcoma; pathways potential; molecular signaling; signaling pathways ... See more keywords
Stochasticity and the limits of molecular signaling in plant development
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.999304
Abstract: Understanding plant development is in part a theoretical endeavor that can only succeed if it is based upon a correctly contrived axiomatic framework. Here I revisit some of the basic assumptions that frame our understanding… read more here.
Keywords: limits molecular; stochasticity limits; plant development; molecular signaling ... See more keywords
The Effects of Antioxidants from Natural Products on Obesity, Dyslipidemia, Diabetes and Their Molecular Signaling Mechanism
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23042056
Abstract: Obesity is a risk factor that leads to the development of other diseases such as dyslipidemia and diabetes. These three metabolic disorders can occur simultaneously, hence, the treatment requires many drugs. Antioxidant compounds have been… read more here.
Keywords: molecular signaling; dyslipidemia diabetes; obesity dyslipidemia; antioxidant compounds ... See more keywords
Huperzine A and Its Neuroprotective Molecular Signaling in Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26216531
Abstract: Huperzine A (HupA), an alkaloid found in the club moss Huperzia serrata, has been used for centuries in Chinese folk medicine to treat dementia. The effects of this alkaloid have been attributed to its ability… read more here.
Keywords: molecular signaling; alzheimer disease; signaling alzheimer; huperzine neuroprotective ... See more keywords
Molecular Signaling Mechanisms for the Antidepressant Effects of NLX-101, a Selective Cortical 5-HT1A Receptor Biased Agonist
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15030337
Abstract: Depression is the most prevalent of the mental illnesses and serotonin (5-hydroxytryptamine, 5-HT) is considered to be the major neurotransmitter involved in its etiology and treatment. In this context, 5-HT1A receptors have attracted interest as… read more here.
Keywords: ht1a; signaling mechanisms; antidepressant effects; molecular signaling ... See more keywords
Molecular-Signaling Pathways of Ginsenosides Rb in Myocardial Ischemia-Reperfusion Injury: A Mini Review
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Medical Sciences"
DOI: 10.7150/ijms.64984
Abstract: Reperfusion injury following myocardial ischemia remained a challenge for optimal treatment of myocardial infarction. Ginsenosides Rb (G-Rb), the primary components of ginsenoside, have been reported to exert cardioprotective effects via numerous mechanisms. G-Rb1 mediate cardioprotective… read more here.
Keywords: reperfusion injury; myocardial ischemia; reperfusion; molecular signaling ... See more keywords