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   Articles with "molecular signature" as a keyword



The appropriate remodeling of extracellular matrix is the key molecular signature in subcutaneous adipose tissue following Roux‐en‐Y gastric bypass

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recommendations! Published in 2019 at "Life Sciences"

DOI: 10.1016/j.lfs.2018.12.051

Abstract: Aims: We sought to reveal the key molecular signature in subcutaneous adipose tissue (scAT) following Roux‐en‐Y gastric bypass (RYGB), through bioinformatics analysis and further verification in vivo. Main methods: We obtained a transcriptome data of… read more here.

Keywords: signature subcutaneous; molecular signature; key molecular; scat ... See more keywords

Molecular signature characters complement taxonomic diagnoses: a bioinformatic approach exemplified by ciliated protists (Ciliophora, Oligotrichea).

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recommendations! Published in 2022 at "Molecular phylogenetics and evolution"

DOI: 10.1016/j.ympev.2022.107433

Abstract: Traditionally, taxa following the botanical or zoological codes of nomenclature are diagnosed mainly by morphological characters, although integrative taxonomy advocates including additional features. While many taxonomic studies include DNA sequence analyses, a systematic integration of… read more here.

Keywords: molecular signature; signature; characters complement; signature characters ... See more keywords

Control of Rectification in Molecular Junctions: Contact Effects and Molecular Signature.

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recommendations! Published in 2017 at "Journal of the American Chemical Society"

DOI: 10.1021/jacs.7b05732

Abstract: Thin layers of oligomers with thickness between 7 and 9 nm were deposited on flat gold electrode surfaces by electrochemical reduction of diazonium reagents, then a Ti(2 nm)/Au top contact was applied to complete a… read more here.

Keywords: rectification; energy; molecular signature; layer ... See more keywords

Molecular signature of progenitor cells isolated from young and adult human hearts

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recommendations! Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-26969-2

Abstract: The loss of endogenous cardiac regenerative capacity within the first week of postnatal life has intensified clinical trials to induce cardiac regeneration in the adult mammalian heart using different progenitor cell types. We hypothesized that… read more here.

Keywords: young adult; adult; progenitor cells; molecular signature ... See more keywords
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Improvement in clinical disease activity index when treatment selection is informed by the tumor necrosis factor-ɑ inhibitor molecular signature response classifier: analysis from the Study to Accelerate Information of Molecular Signatures in Rheumatoid Arthritis.

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recommendations! Published in 2022 at "Expert opinion on biological therapy"

DOI: 10.1080/14712598.2022.2066972

Abstract: BACKGROUND A blood-based molecular signature response classifier (MSRC) predicts non-response to tumor necrosis factor-ɑ inhibitors (TNFi) in rheumatoid arthritis (RA). RESEARCH DESIGN AND METHODS This is an interim analysis of data collected in the Study… read more here.

Keywords: molecular signature; disease activity; disease; response ... See more keywords

Patient outcomes improve when a molecular signature test guides treatment decision-making in rheumatoid arthritis

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recommendations! Published in 2022 at "Expert Review of Molecular Diagnostics"

DOI: 10.1080/14737159.2022.2140586

Abstract: ABSTRACT Background The molecular signature response classifier (MSRC) predicts tumor necrosis factor-ɑ inhibitor (TNFi) non-response in rheumatoid arthritis. This study evaluates decision-making, validity, and utility of MSRC testing. Methods This comparative cohort study compared an… read more here.

Keywords: molecular signature; signature; cdai; rheumatoid arthritis ... See more keywords

PATH-65. MOLECULAR SIGNATURE OF FAT1 RELATED MOLECULES IN GLIOMAS IN THE CONTEXT OF THE WHO 2016 CLASSIFICATION

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recommendations! Published in 2019 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noz175.660

Abstract: Glioblastoma (GBM, WHO grade-IV) being the most malignant and aggressive form of glioma remains a major clinical challenge, with an overall 5-year survival rate of only 9.8%. Till recently, glioma diagnosis and grading were solely… read more here.

Keywords: glioma; molecular signature; fat1 related; fat1 ... See more keywords

The local molecular signature of human peripheral neuropathic pain

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recommendations! Published in 2024 at "Pain"

DOI: 10.1097/j.pain.0000000000003472

Abstract: Supplemental Digital Content is Available in the Text. Combining pain-profiling with RNA sequencing and immunohistochemistry of Morton's neuroma and noninjured nerves, we identify an ongoing role for intraneural inflammation in chronic peripheral neuropathic pain. read more here.

Keywords: local molecular; pain; molecular signature; peripheral neuropathic ... See more keywords

Molecular Signature of Tumor-Associated High Endothelial Venules That Can Predict Breast Cancer Survival

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recommendations! Published in 2022 at "Cancer Immunology Research"

DOI: 10.1158/2326-6066.cir-21-0369

Abstract: The authors identify a molecular signature of breast tumor–associated high endothelial venules, which correlate with presence of tertiary lymphoid structures and survival, suggesting the signature may provide information for treatment selection and determining prognosis. read more here.

Keywords: molecular signature; tumor associated; signature; high endothelial ... See more keywords

A Molecular Signature of Two Long Non-Coding RNAs in Peripheral Blood Predicts Acute Renal Allograft Rejection

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recommendations! Published in 2017 at "Cellular Physiology and Biochemistry"

DOI: 10.1159/000485451

Abstract: Background/Aims: Acute rejection (AR) is a major complication post renal transplantation, with no widely-accepted non-invasive biomarker. This study aimed to explore the expression profiles of long non-coding RNAs (lncRNAs) in the peripheral blood (PB) of… read more here.

Keywords: signature two; coding rnas; molecular signature; long non ... See more keywords

A specific molecular signature in SARS-CoV-2–infected kidney biopsies

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recommendations! Published in 2023 at "JCI Insight"

DOI: 10.1172/jci.insight.165192

Abstract: Acute kidney injury is one of the most important complications in patients with COVID-19 and is considered a negative prognostic factor with respect to patient survival. The occurrence of direct infection of the kidney by… read more here.

Keywords: molecular signature; kidney; cov infected; specific molecular ... See more keywords