Articles with "molecular stratification" as a keyword



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Molecular Stratification of Colorectal Cancer: Moving from the Laboratory to Clinical Practice

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Published in 2017 at "Current Colorectal Cancer Reports"

DOI: 10.1007/s11888-017-0347-8

Abstract: Purpose of ReviewColorectal cancer is increasingly recognised as a heterogeneous disease entity, and subtyping is carried out based upon clinical and pathological characteristics, individual somatic gene mutations and, more recently, gene expression profiling. This paper… read more here.

Keywords: molecular stratification; colorectal cancer; stratification colorectal; cancer ... See more keywords
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DNA methylation‐based classification of glioneuronal tumours synergises with histology and radiology to refine accurate molecular stratification

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Published in 2023 at "Neuropathology and Applied Neurobiology"

DOI: 10.1111/nan.12894

Abstract: Glioneuronal tumours (GNTs) are poorly distinguished by their histology and lack robust diagnostic indicators. Previously, we showed that common GNTs comprise two molecularly distinct groups, correlating poorly with histology. To refine diagnosis, we constructed a… read more here.

Keywords: radiology; glioneuronal tumours; molecular stratification; methylation based ... See more keywords
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Toward Molecular Stratification and Precision Medicine in Systemic Sclerosis

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Published in 2022 at "Frontiers in Medicine"

DOI: 10.3389/fmed.2022.911977

Abstract: Systemic sclerosis (SSc), a complex multi-systemic disease characterized by immune dysregulation, vasculopathy and fibrosis, is associated with high mortality. Its pathogenesis is only partially understood. The heterogenous pathological processes that define SSc and its stages… read more here.

Keywords: systemic sclerosis; molecular stratification; stratification; precision medicine ... See more keywords
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Molecular stratification of high-grade urothelial carcinoma by immunohistochemistry with its histomorphological and clinical correlation

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Published in 2022 at "Indian Journal of Pathology and Microbiology"

DOI: 10.4103/ijpm.ijpm_95_21

Abstract: Introduction: Urothelial carcinoma poses a significant cause of morbidity and mortality. The recent classification of Tumors of Urinary System by World Health Organization fourth edition) has elucidated its molecular subtypes and its associated prognostic significance.… read more here.

Keywords: grade urothelial; molecular stratification; high grade; urothelial carcinoma ... See more keywords