The added prognostic value of radiological phenotype combined with clinical features and molecular subtype in anaplastic gliomas
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-018-03072-0
Abstract: PurposeTo determine whether radiological phenotype can improve the predictive performance of the risk model based on molecular subtype and clinical risk factors in anaplastic glioma patients.MethodsThis retrospective study was approved by our institutional review board… read more here.
Keywords: rrs; prognostic value; molecular subtype; model ... See more keywords
Identification of a correlation between the sonographic appearance and molecular subtype of invasive breast cancer: A review of 311 cases.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical imaging"
DOI: 10.1016/j.clinimag.2018.10.020
Abstract: PURPOSE To identify the ultrasound and clinical features related to the different molecular subtypes of invasive breast cancer. METHODS Sonographic and clinical data of 311 surgically confirmed breast cancer cases were retrospectively reviewed and compared… read more here.
Keywords: molecular subtype; invasive breast; breast; breast cancer ... See more keywords
Molecular subtype diagnosis of endometrial carcinoma: comparison of NGS panel and ProMisE classifier.
Sign Up to like & getrecommendations! Published in 2021 at "Human pathology"
DOI: 10.1016/j.humpath.2021.02.006
Abstract: OBJECTIVES The Cancer Genome Atlas-based molecular classification of endometrial carcinoma (EC) has the potential to better identify those patients whose disease is likely to behave differently than predicted when using traditional risk stratification, however, the… read more here.
Keywords: molecular subtype; ngs panel; subtype diagnosis;
NIMG-08. PREDICTION OF LOWER-GRADE GLIOMA MOLECULAR SUBTYPES USING DEEP LEARNING
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-oncology"
DOI: 10.1093/neuonc/noaa215.621
Abstract: It is useful to know the molecular subtype of lower-grade gliomas (LGG) when deciding on a treatment strategy. This study aims to diagnose this preoperatively. A deep learning model was developed to predict the 3-group… read more here.
Keywords: deep learning; molecular subtype; model; lower grade ... See more keywords
Distinct genetic alterations and luminal molecular subtype in nested variant of urothelial carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Histopathology"
DOI: 10.1111/his.13958
Abstract: Nested variant of urothelial carcinoma (NVUC) is rare, and only a few small series exist. Molecular characteristics and the classifying marker profile as well as therapeutic targets of this specific variant are mostly unknown. The… read more here.
Keywords: molecular subtype; variant urothelial; nested variant; urothelial carcinoma ... See more keywords
Proteomics profiling reveals a distinct high-risk molecular subtype of hypertrophic cardiomyopathy
Sign Up to like & getrecommendations! Published in 2022 at "Heart"
DOI: 10.1136/heartjnl-2021-320729
Abstract: Objective Hypertrophic cardiomyopathy (HCM) is a heterogeneous disease, likely encompassing several subtypes of disease with distinct biological mechanisms (ie, molecular subtypes). Current models based solely on clinical data have yielded limited accuracy in predicting the… read more here.
Keywords: hypertrophic cardiomyopathy; molecular subtypes; risk; proteomics profiling ... See more keywords
Abstract PS1-33: Molecular subtype and clinical stage influenced axillary lymph node response in breast cancer patients with breast pathological complete remission after neoadjuvant therapy
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs20-ps1-33
Abstract: Background: It is unknown whether molecular subtype is associated with axillary lymph node (ALN) status (ypN) after neoadjuvant therapy (NAT) in breast cancer patients who achieved breast pathological complete remission (pCR), especially for patients with… read more here.
Keywords: molecular subtype; breast cancer; clinical stage; cancer ... See more keywords
Molecular subtype assay to reveal anti-EGFR response sub-clones in colorectal cancer (CRC).
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.4_suppl.658
Abstract: 658Background: We previously stratified CRC into five intrinsic gene expression subtypes (CRCAssigner) and four consensus molecular subtypes (CMS1-4) using expensive and time-consuming microarray/R... read more here.
Keywords: reveal anti; molecular subtype; subtype assay; anti egfr ... See more keywords
Molecular subtype variation within metastasis of urothelial carcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.6_suppl.471
Abstract: 471Background: Molecular subtyping of cancer based on gene expression is a new prognostic tool with potential to guide treatment in the future. Urothelial carcinoma is one such cancer for which num... read more here.
Keywords: molecular subtype; carcinoma; subtype variation; within metastasis ... See more keywords
Breast Cancer Molecular Subtype Prediction on Pathological Images with Discriminative Patch Selection and Multi-Instance Learning
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.858453
Abstract: Molecular subtypes of breast cancer are important references to personalized clinical treatment. For cost and labor savings, only one of the patient’s paraffin blocks is usually selected for subsequent immunohistochemistry (IHC) to obtain molecular subtypes.… read more here.
Keywords: subtype prediction; breast cancer; molecular subtype; patch ... See more keywords
CYP1B1: A Novel Molecular Biomarker Predicts Molecular Subtype, Tumor Microenvironment, and Immune Response in 33 Cancers
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14225641
Abstract: Simple Summary Cytochrome P450 Family 1 Subfamily B Member 1 (CYP1B1) is a critical metabolic enzyme of melatonin. Although melatonin has been identified to exhibit tumor suppressing activity, the role and mechanism of the clinical… read more here.
Keywords: subtype tumor; cyp1b1; tumor; cancer ... See more keywords