Articles with "molecular subtyping" as a keyword



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Molecular subtyping of gastric cancer with respect to the growth pattern of lymph-node metastases

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Published in 2019 at "Journal of Cancer Research and Clinical Oncology"

DOI: 10.1007/s00432-019-03029-4

Abstract: Gastric cancer is the third leading cause of cancer-related death. Recently, innovative diagnostic and prognostic molecular subtypes have been proposed. We revealed that extranodal extension (ENE) of lymph-node metastases independently influences survival. Therefore, the aim… read more here.

Keywords: gastric cancer; molecular subtyping; cancer; lymph node ... See more keywords
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The clinical impacts of molecular subtyping by multigene assay on hormone receptor-positive breast cancers

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Published in 2021 at "Journal of the Chinese Medical Association"

DOI: 10.1097/jcma.0000000000000657

Abstract: Background: Multigene assays, such as MammaPrint and BluePrint, provide additional information other than conventional immunohistochemistry (IHC) to help making decision of treatment. This study aims to compare the clinical correlation between molecular subtyping (MS) versus… read more here.

Keywords: receptor positive; hormone receptor; molecular subtyping; positive breast ... See more keywords
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Automated Molecular Subtyping of Breast Carcinoma Using Deep Learning Techniques

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Published in 2023 at "IEEE Journal of Translational Engineering in Health and Medicine"

DOI: 10.1109/jtehm.2023.3241613

Abstract: Objective: Molecular subtyping is an important procedure for prognosis and targeted therapy of breast carcinoma, the most common type of malignancy affecting women. Immunohistochemistry (IHC) analysis is the widely accepted method for molecular subtyping. It… read more here.

Keywords: automated molecular; breast; breast carcinoma; deep learning ... See more keywords
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Molecular subtyping of mammary‐like adenocarcinoma of the vulva shows molecular similarity to breast carcinomas

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Published in 2017 at "Histopathology"

DOI: 10.1111/his.13239

Abstract: Mammary‐like adenocarcinoma (MLA) of the vulva is thought to be derived from vulvar mammary‐like glands. The aim of this study was to characterize a series of MLAs by using an immunohistochemical algorithm that identifies the… read more here.

Keywords: breast; mammary like; like adenocarcinoma; molecular subtyping ... See more keywords
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Molecular subtyping of European swine influenza viruses and scaling to high-throughput analysis

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Published in 2018 at "Virology Journal"

DOI: 10.1186/s12985-018-0920-z

Abstract: BackgroundSwine influenza is a respiratory infection of pigs that may have a significant economic impact in affected herds and pose a threat to the human population since swine influenza A viruses (swIAVs) are zoonotic pathogens.… read more here.

Keywords: swine influenza; influenza viruses; influenza; molecular subtyping ... See more keywords
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Molecular subtyping of metastatic urothelial bladder cancer.

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Published in 2017 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2017.35.6_suppl.326

Abstract: 326Background: TCGA molecular sybtyping is established in metastatic urothelial bladder cancer (UBC). It remains unclear if it is of prognostic importance with chemotherapy in metastatic UBC. Data into immune therapy suggests TCGA subtyping is predictive… read more here.

Keywords: bladder cancer; urothelial bladder; molecular subtyping; cancer ... See more keywords
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Integrated bioinformatics analysis uncovers characteristic genes and molecular subtyping system for endometriosis

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Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.932526

Abstract: Objective: Endometriosis is a chronic inflammatory estrogen-dependent disease with the growth of endometrial tissues outside the uterine cavity. Nevertheless, the etiology of endometriosis is still unclear. Integrated bioinformatics analysis was implemented to reveal the molecular… read more here.

Keywords: endometriosis; bioinformatics analysis; analysis; integrated bioinformatics ... See more keywords
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Immunohistochemistry-based molecular subtyping of triple-negative breast cancer and its prognostic significance

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Published in 2023 at "Pathology and Oncology Research"

DOI: 10.3389/pore.2023.1611162

Abstract: Background: Immunohistochemistry (IHC)-based protein markers representing molecular subtypes are of great value for routine use. This study aimed to evaluate the frequency distributions of the molecular subtypes of triple-negative breast cancer (TNBC) using IHC-based surrogate… read more here.

Keywords: triple negative; breast cancer; based molecular; molecular subtyping ... See more keywords
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Molecular Subtyping and Prognostic Assessment Based on Tumor Mutation Burden in Patients with Lung Adenocarcinomas

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Published in 2019 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms20174251

Abstract: The distinct molecular subtypes of lung cancer are defined by monogenic biomarkers, such as EGFR, KRAS, and ALK rearrangement. Tumor mutation burden (TMB) is a potential biomarker for response to immunotherapy, which is one of… read more here.

Keywords: tumor mutation; lung adenocarcinomas; molecular subtyping; mutation burden ... See more keywords
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Are We Ready to Implement Molecular Subtyping of Bladder Cancer in Clinical Practice? Part 2: Subtypes and Divergent Differentiation

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23147844

Abstract: Following several attempts to achieve a molecular stratification of bladder cancer (BC) over the last decade, a “consensus” classification has been recently developed to provide a common base for the molecular classification of bladder cancer… read more here.

Keywords: bladder; practice; molecular subtyping; implement molecular ... See more keywords
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[Early identification of a clustered epidemic of typhoid fever through pathogen molecular subtyping monitoring].

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Published in 2022 at "Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]"

DOI: 10.3760/cma.j.cn112150-20210430-00432

Abstract: Objective: To identify a suspected clustered Typhoid fever by whole genome sequencing(WGS) and pulsed field gel electrophoresis (PFGE) subtyping. Methods: The nature of the epidemic was determined by combination of subtyping results of isolates and… read more here.

Keywords: typhoid; typhoid fever; molecular subtyping; early identification ... See more keywords