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   Articles with "molecular testing" as a keyword



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Molecular Testing for the World Health Organization Classification of Central Nervous System Tumors: A Review.

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recommendations! Published in 2024 at "JAMA oncology"

DOI: 10.1001/jamaoncol.2024.5506

Abstract: Importance Molecular techniques, including next-generation sequencing, genomic copy number profiling, fusion transcript detection, and genomic DNA methylation arrays, are now indispensable tools for the workup of central nervous system (CNS) tumors. Yet there remains a… read more here.

Keywords: classification; cns tumors; central nervous; nervous system ... See more keywords

Ancillary molecular testing of indeterminate thyroid nodules

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recommendations! Published in 2018 at "Cancer Cytopathology"

DOI: 10.1002/cncy.22012

Abstract: Cytological specimens from thyroid nodules are increasingly being adopted as the first available material for cost effectively managing patients in the era of personalized medicine. Cytology aspirates not only play a central role in providing… read more here.

Keywords: thyroid nodules; indeterminate thyroid; molecular testing; ancillary molecular ... See more keywords

BRAF molecular testing in cytopathology: Implications for diagnosis, prognosis, and targeted therapeutics

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recommendations! Published in 2019 at "Cancer Cytopathology"

DOI: 10.1002/cncy.22209

Abstract: The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that transduces signals from the cell membrane through the mitogen-activated protein kinase (MAPK) phosphorylation cascade to promote global cellular responses including growth, proliferation, survival,… read more here.

Keywords: molecular testing; braf; cytopathology; braf molecular ... See more keywords
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Diagnostic efficacy and molecular testing by combined fine‐needle aspiration and core needle biopsy in patients with a lung nodule

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recommendations! Published in 2020 at "Cancer Cytopathology"

DOI: 10.1002/cncy.22234

Abstract: Combined image‐guided fine‐needle aspiration biopsy (FNA) and core needle biopsy (CNB) has become the standard of care for diagnosis and/or molecular testing for patients with a solitary lung nodule at our institution. Our purpose was… read more here.

Keywords: biopsy; needle aspiration; core needle; needle biopsy ... See more keywords

Overview and update on molecular testing in non‐small cell lung carcinoma utilizing endobronchial ultrasound‐guided transbronchial needle aspiration (EBUS‐TBNA) samples

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recommendations! Published in 2022 at "Diagnostic Cytopathology"

DOI: 10.1002/dc.25019

Abstract: Lung carcinoma remains one of the most frequent and aggressive human neoplasms. Fortunately, in the last decades, the increasing knowledge of the molecular mechanisms leading to cancer development has allowed the use of targeted therapies… read more here.

Keywords: molecular testing; lung carcinoma; non small; testing non ... See more keywords

Molecular testing in fine‐needle aspiration of thyroid nodules

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recommendations! Published in 2022 at "Diagnostic Cytopathology"

DOI: 10.1002/dc.25035

Abstract: Thyroid nodules are commonly faced by clinicians as palpable nodules or incidentally identified on imaging. Nodules that are found to be suspicious by imaging can be biopsied by fine needle aspiration, which can yield material… read more here.

Keywords: molecular testing; thyroid nodules; testing fine; fine needle ... See more keywords

Principles of molecular testing for hereditary cancer

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recommendations! Published in 2022 at "Genes"

DOI: 10.1002/gcc.23048

Abstract: Molecular testing for hereditary cancers has rapidly advanced over the past two decades. Next‐generation sequencing has been widely adopted, which has made molecular testing increasingly accessible, and large gene panels are now routinely used in… read more here.

Keywords: molecular testing; principles molecular; etiology; hereditary cancer ... See more keywords

Molecular Testing in Gliomas: What is Necessary in Routine Clinical Practice?

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recommendations! Published in 2024 at "Current Oncology Reports"

DOI: 10.1007/s11912-024-01602-w

Abstract: A number of molecular characteristics are essential for accurate diagnosis and prognostication in glioma. The 2021 WHO classification of brain tumors and recent Food and Drug Administration (FDA) pathology agnostic drug approvals highlight the importance… read more here.

Keywords: testing gliomas; routine clinical; necessary routine; gliomas necessary ... See more keywords
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Molecular testing of different cytologic preparations in patients with advanced lung adenocarcinoma: which yields the best results?

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recommendations! Published in 2017 at "Journal of the American Society of Cytopathology"

DOI: 10.1016/j.jasc.2016.06.002

Abstract: INTRODUCTION This study constitutes the first systematic comparison of molecular results between different cytology preparations in patients with lung adenocarcinoma undergoing testing for EGFR, KRAS, and BRAF mutations. MATERIALS AND METHODS 115 archival cytology preparations… read more here.

Keywords: lung adenocarcinoma; preparations patients; tumor purity; molecular testing ... See more keywords
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A review of the FDA-approved molecular testing platforms for human papillomavirus.

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recommendations! Published in 2019 at "Journal of the American Society of Cytopathology"

DOI: 10.1016/j.jasc.2019.06.001

Abstract: The advent of US Food and Drug Administration (FDA)-approved molecular testing for human papillomavirus (HPV) has resulted in a dramatic shift from cytological testing alone to a combination of cytology and molecular testing for primary… read more here.

Keywords: human papillomavirus; molecular testing; approved molecular; testing platforms ... See more keywords

P2.15-20 Educating The Multispecialty Team on Molecular Testing Related to Immunotherapy

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recommendations! Published in 2018 at "Journal of Thoracic Oncology"

DOI: 10.1016/j.jtho.2018.08.1462

Abstract: Learner Specialties: US Learners by Region: Educating The Multispecialty Team on Molecular Testing Related to Immunotherapy Tara Perloff1, Jennie Crews MD2, Dan Raz MD3, Lorna Lucas MSM1, Pam Rattananont MPH1, Wendy Turell PhD4, Jeffrey P.… read more here.

Keywords: molecular testing; testing related; multispecialty team; related immunotherapy ... See more keywords