Efficient Release of Affinity-Captured Cells Using a Coiled-Coil-Based Molecular Trigger.
Sign Up to like & getrecommendations! Published in 2017 at "Macromolecular bioscience"
DOI: 10.1002/mabi.201600330
Abstract: Affinity-based cell separation is label-free and highly specific, but it is difficult to efficiently and gently release affinity-captured cells due to the multivalent nature of cell-material interactions. To address this challenge, we have developed a… read more here.
Keywords: molecular trigger; affinity; captured cells; coiled coil ... See more keywords
A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo
Sign Up to like & getrecommendations! Published in 2018 at "Nature Biotechnology"
DOI: 10.1038/nbt.4071
Abstract: Nanoscale robots have potential as intelligent drug delivery systems that respond to molecular triggers. Using DNA origami we constructed an autonomous DNA robot programmed to transport payloads and present them specifically in tumors. Our nanorobot… read more here.
Keywords: molecular trigger; dna; cancer; dna nanorobot ... See more keywords