Molecular tuning of electroreception in sharks and skates
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DOI: 10.1038/s41586-018-0160-9
Abstract: Ancient cartilaginous vertebrates, such as sharks, skates and rays, possess specialized electrosensory organs that detect weak electric fields and relay this information to the central nervous system1–4. Sharks exploit this sensory modality for predation, whereas… read more here.
Keywords: voltage; potassium channels; molecular tuning; electrosensory cells ... See more keywords
Molecular Tuning of IR-786 for Improved Brown Adipose Tissue Imaging
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DOI: 10.3390/ijms232213756
Abstract: To overcome the limitations of brown adipose tissue (BAT) imaging with MRI and PET/CT, near-infrared (NIR) fluorescence imaging has been utilized in living animals because it is highly sensitive, noninvasive, nonradioactive, and cost-effective. To date,… read more here.
Keywords: tuning 786; molecular tuning; adipose tissue; bat ... See more keywords
Molecular Tuning of IR-786 for Improved Tumor Imaging and Photothermal Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14030676
Abstract: A tumor-targeted near-infrared (NIR) fluorophore CA800Cl was developed based on commercially available IR-786 by modulating its physicochemical properties. IR-786, a hydrophobic cationic heptamethine cyanine fluorophore, was previously recognized as a mitochondria-targeting NIR agent with excellent… read more here.
Keywords: 786 improved; tuning 786; improved tumor; molecular tuning ... See more keywords