PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum
Sign Up to like & getrecommendations! Published in 2021 at "Acta Neuropathologica"
DOI: 10.1007/s00401-021-02354-8
Abstract: Large-scale molecular profiling studies in recent years have shown that central nervous system (CNS) tumors display a much greater heterogeneity in terms of molecularly distinct entities, cellular origins and genetic drivers than anticipated from histological… read more here.
Keywords: patz1 fusions; spectrum; fusions define; molecularly distinct ... See more keywords
Immature CD8 Single-Positive Thymocytes Are a Molecularly Distinct Subpopulation, Selectively Dependent on BRD4 for Their Differentiation
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.06.007
Abstract: SUMMARY T cell differentiation in the thymus proceeds in an ordered sequence of developmental events characterized by variable expression of CD4 and CD8 coreceptors. Here, we report that immature single-positive (ISP) thymocytes are molecularly distinct… read more here.
Keywords: thymocytes molecularly; subpopulation; differentiation; single positive ... See more keywords