Facile fabrication of polypyrrole-coated silver nanoparticles: A novel and efficient surface-enhanced Raman scattering support for molecule detection
Sign Up to like & getrecommendations! Published in 2019 at "Optics and Laser Technology"
DOI: 10.1016/j.optlastec.2019.105705
Abstract: Abstract Conducting polymer coated noble metal particles, particularly polypyrrole (PPy)-coated silver (Ag) nanoparticles can be efficient and unprecedented surface-enhanced Raman scattering (SERS) electrodes. Here in this work, a very simple and robust strategy has been… read more here.
Keywords: spectroscopy; molecule detection; ppy coated; coated nanoparticles ... See more keywords
Combination of bidirectional strand displacement amplification with single-molecule detection for multiplexed DNA glycosylases assay.
Sign Up to like & getrecommendations! Published in 2021 at "Talanta"
DOI: 10.1016/j.talanta.2021.122805
Abstract: DNA glycosylases can initiate base excision repair pathway to repair endogenous DNA base damages for the maintenance of genome stability. Multiple DNA glycosylases exhibit abnormal in various diseases, and the simultaneous measurement of different DNA… read more here.
Keywords: molecule detection; single molecule; dna glycosylases; dna ... See more keywords
Super-High-Resolution Densitometry by Optical Trapping of a Single-Molecularly Imprinted Polymer Particle for Subsingle Molecule Detection.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c04168
Abstract: In this study, for the first time, we have shown that the single nano-/microparticle trapping ability of optical tweezers combined with the high selectivity of molecularly imprinted polymers (MIPs) provides an indispensable molecular-level instrument for… read more here.
Keywords: subsingle molecule; trapping single; molecularly imprinted; molecule ... See more keywords
Translocation of Specific DNA Nanocarrier through an Ultrasmall Nanopipette: Toward Single-Protein-Molecule Detection with Superior Signal-to-Noise Ratio.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.2c06303
Abstract: The use of functional DNA nanostructures as carriers to ship proteins through solid-state nanopores has recently seen substantial growth in single-protein-molecule detection (SPMD), driven by the potential of this methodology and implementations that it may… read more here.
Keywords: single protein; dna; protein molecule; detection ... See more keywords
An Integrated Amplification-Free Digital CRISPR/Cas-Assisted Assay for Single Molecule Detection of RNA.
Sign Up to like & getrecommendations! Published in 2023 at "ACS nano"
DOI: 10.1021/acsnano.2c10143
Abstract: Conventional nucleic acid detection technologies usually rely on amplification to improve sensitivity, which has drawbacks, such as amplification bias, complicated operation, high requirements for complex instruments, and aerosol pollution. To address these concerns, we developed… read more here.
Keywords: single molecule; crispr; amplification; detection ... See more keywords
Hybrid Plasmonic Nanostructures for Enhanced Single-Molecule Detection Sensitivity
Sign Up to like & getrecommendations! Published in 2023 at "ACS Nano"
DOI: 10.1021/acsnano.3c00576
Abstract: Biosensing applications based on fluorescence detection often require single-molecule sensitivity in the presence of strong background signals. Plasmonic nanoantennas are particularly suitable for these tasks, as they can confine and enhance light in volumes far… read more here.
Keywords: single molecule; sensitivity; detection sensitivity; detection ... See more keywords
Single-molecule Detection of Ultrafast Biomolecular Dynamics with Nanophotonics.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c09387
Abstract: Single-molecule Förster resonance energy transfer (FRET) is a versatile technique for probing the structure and dynamics of biomolecules even in heterogeneous ensembles. However, because of the limited fluorescence brightness per molecule and the relatively long… read more here.
Keywords: biomolecular dynamics; molecule; molecule detection; detection ultrafast ... See more keywords
Unique Electrical Signature of Phosphate for Specific Single-Molecule Detection of Peptide Phosphorylation.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c05787
Abstract: Single-molecule measurements of biomaterials bring novel insights into cellular events. For almost all of these events, post-translational modifications (PTMs), which alter the properties of proteins through their chemical modifications, constitute essential regulatory mechanisms. However, suitable… read more here.
Keywords: single molecule; detection peptide; methodology; molecule ... See more keywords
Simultaneous single-molecule detection of the acetyltransferase and crotonyltransferase activities of histone acetylation writer p300.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc05449j
Abstract: We demonstrate for the first time the simultaneous measurement of the acetyltransferase (HAT) and crotonyltransferase (HCT) activities of histone acetylation writer p300 by integrating antibody-based fluorescence labeling with single molecule detection. This methods exhibits good… read more here.
Keywords: histone acetylation; single molecule; writer p300; activities histone ... See more keywords
Single-molecule detection with enhanced Raman scattering of tungsten oxide nanostructure.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d2nr03596k
Abstract: We have found that tungsten oxide nanorods have a very large enhancement effect on Raman scattering. The nanorods with adsorbed 12CO and 13CO at the ratio of 1 : 1 were dispersed on a Si substrate and… read more here.
Keywords: single molecule; raman scattering; molecule detection; tungsten oxide ... See more keywords
Single-molecule detection of deoxyribonucleoside triphosphates in microdroplets
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkz611
Abstract: Abstract A new approach to single-molecule DNA sequencing in which dNTPs, released by pyrophosphorolysis from the strand to be sequenced, are captured in microdroplets and read directly could have substantial advantages over current sequence-by-synthesis methods;… read more here.
Keywords: molecule; single molecule; deoxyribonucleoside triphosphates; molecule detection ... See more keywords