Ensemble sensing using single-molecule DNA copolymers.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.0c02196
Abstract: While single-molecule sensing has offered ultimate mass sensitivity at the precision of individual molecules, it requires longer time to detect analytes at lower concentrations when analyte binding to single-molecule probes becomes diffusion-limited. Here, we solved… read more here.
Keywords: molecule; single molecule; ensemble sensing; using single ... See more keywords
High Spatial Resolution of Ultrathin Covalent Organic Framework Nanopores for Single-Molecule DNA Sensing.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c01708
Abstract: Ultrathin nanosheets of two-dimensional covalent organic frameworks covered a quartz nanopipette and then acted as a nanopore device for single-molecule DNA sensing. Our results showed that a single DNA homopolymer as short as 6 bases… read more here.
Keywords: single molecule; dna; dna sensing; covalent organic ... See more keywords
Single-Molecule DNA Extension in Rectangular and Square Profile Nanochannels in the Extended de Gennes Regime
Sign Up to like & getrecommendations! Published in 2020 at "Macromolecules"
DOI: 10.1021/acs.macromol.9b02249
Abstract: Experiments measuring the extension of moderately confined double-stranded DNA within nanochannels have consistently shown a stronger scaling relationship between extension length and nanochannel c... read more here.
Keywords: single molecule; dna; dna extension; molecule dna ... See more keywords