Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Lipid Research"
DOI: 10.1194/jlr.m081851
Abstract: apoE is the primary lipid carrier within the CNS and the strongest genetic risk factor for late onset Alzheimer’s disease (AD). apoE is primarily lipidated via ABCA1, and both are under transcriptional regulation by the… read more here.
Keywords: lxr; abca1 apoe; small molecule; molecule inducers ... See more keywords