Articles with "molecule mediated" as a keyword



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Small molecule-mediated co-assembly of amyloid-β oligomers reduces neurotoxicity through promoting non-fibrillar aggregation†

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Published in 2020 at "Chemical Science"

DOI: 10.1039/d0sc00392a

Abstract: Amyloid-β (Aβ) oligomers, particularly low molecular weight (LMW) oligomers, rather than fibrils, contribute very significantly to the onset and progression of Alzheimer's Disease (AD). However, due to the inherent heterogeneity and metastability of oligomers, most… read more here.

Keywords: mediated assembly; small molecule; non fibrillar; molecule mediated ... See more keywords