Single-Molecule SERS Discrimination of Proline from Hydroxyproline Assisted by a Deep Learning Model
Sign Up to like & getrecommendations! Published in 2025 at "Nano Letters"
DOI: 10.1021/acs.nanolett.5c01177
Abstract: Discriminating low-abundance hydroxylation is a crucial and unmet need for early disease diagnostics and therapeutic development due to the small hydroxyl group with 17.01 Da. While single-molecule surface-enhanced Raman spectroscopy (SERS) sensors can detect hydroxylation,… read more here.
Keywords: molecule; proline hydroxyproline; model; molecule sers ... See more keywords
Pattern Recognition Directed Assembly of Plasmonic Gap Nanostructures for Single-Molecule SERS.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.2c05150
Abstract: Gold nanocubes (AuNCs) with tunable localized surface plasmon resonance properties are good candidates for plasmonic gap nanostructures (PGNs) with hot spots (areas with intense electric field localization). Nevertheless, it remains challenging to create shape-controllable nanogaps… read more here.
Keywords: single molecule; gap nanostructures; molecule; molecule sers ... See more keywords
High-Speed Spectral Characterization of Single-Molecule SERS Fluctuations.
Sign Up to like & getrecommendations! Published in 2023 at "ACS nano"
DOI: 10.1021/acsnano.2c12457
Abstract: The concept of plasmonic "hotspots" is central to the broad field of nanophotonics. In surface-enhanced Raman scattering (SERS), hotspots can increase Raman scattering efficiency by orders of magnitude. Hotspot dimensions may range from a few… read more here.
Keywords: high speed; speed; single molecule; sers fluctuations ... See more keywords