A Small-Molecule Splicing Modulator Targets Spliceosome-Mutant Cells.
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DOI: 10.1158/2159-8290.cd-rw2018-038
Abstract: The small molecule H3B-8800 binds to and modulates the SF3b complex to kill spliceosome-mutant cells. read more here.
Keywords: splicing modulator; mutant cells; molecule splicing; small molecule ... See more keywords