What can be learned about the enzyme ATPase from single-molecule studies of its subunit F1?
Sign Up to like & getrecommendations! Published in 2017 at "Quarterly Reviews of Biophysics"
DOI: 10.1017/s0033583517000129
Abstract: Abstract We summarize the different types of single molecule experiments on the F1 component of FOF1-ATP Synthase and what has been learned from them. We also describe results from our recent studies on interpreting the… read more here.
Keywords: molecule; single molecule; atpase single; molecule studies ... See more keywords
Single-molecule studies of amyloid proteins: from biophysical properties to diagnostic perspectives
Sign Up to like & getrecommendations! Published in 2020 at "Quarterly Reviews of Biophysics"
DOI: 10.1017/s0033583520000086
Abstract: Abstract In neurodegenerative diseases, a wide range of amyloid proteins or peptides such as amyloid-beta and α-synuclein fail to keep native functional conformations, followed by misfolding and self-assembling into a diverse array of aggregates. The… read more here.
Keywords: single molecule; amyloid proteins; studies amyloid; proteins biophysical ... See more keywords
Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells.
Sign Up to like & getrecommendations! Published in 2017 at "Nature chemical biology"
DOI: 10.1038/nchembio.2458
Abstract: Enhancing production of the anti-inflammatory cytokine interleukin-10 (IL-10) is a promising strategy to suppress pathogenic inflammation. To identify new mechanisms regulating IL-10 production, we conducted a phenotypic screen for small molecules that enhance IL-10 secretion… read more here.
Keywords: identify cdk8; small molecule; cdk8 cdk19; cdk8 ... See more keywords
Nitrogen as a Probe Molecule for the IR Studies of the Heterogeneity of OH Groups in Zeolites
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DOI: 10.3390/molecules26206261
Abstract: One of the methods of IR studies of the heterogeneity of Si–OH–Al groups in zeolites is the investigation of the frequency shift of the band of free OH bands restored upon the adsorption of ammonia… read more here.
Keywords: studies heterogeneity; heterogeneity; probe molecule; groups zeolites ... See more keywords