Checkpoint molecules coordinately restrain hyperactivated effector T cells in the tumor microenvironment
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DOI: 10.1080/2162402x.2019.1708064
Abstract: ABSTRACT The immune checkpoint blockade (ICB) immunotherapy has prolonged overall survival for cancer patients but the response rates are low. The resistance to ICB is likely due to compensatory upregulation of additional immune inhibitory molecules.… read more here.
Keywords: checkpoint; molecules coordinately; cd8 cells; checkpoint molecules ... See more keywords